Comparison of hemostatic properties between collagen and synthetic buttress materials used in staple line reinforcement in a swine splenic hemorrhage model.

Introduction: The use of staplers in gastrointestinal surgery is widespread, especially in advanced laparoscopic procedures. Staple line reinforcement with a buttress reduces bleeding and associated complications through a combination of factors. The intrinsic hemostatic properties of buttress materials have not been examined.

Novel propylene oxide-treated bovine pericardium as soft tissue repair material and potential scaffold for tissue engineering.

In contrast with autographic or allographic repair materials, the use of a xenographic soft tissue repair material could improve patient outcomes following surgery, since such a material would not require a second surgical site and could reduce the risk of human-to-human disease transmission. Veritas(c) Collagen Matrix (Veritas) is a novel, non-crosslinked soft tissue repair material derived from bovine pericardium. Physical property testing shows this material is strong, malleable, of uniform thickness, and easily sutureable.

Manipulation of remodeling pathways to enhance the mechanical properties of a tissue engineered blood vessel.

There is a current need for a small diameter vascular graft due to the limited supply of autogenous grafts and the failure of synthetic grafts due to thrombosis and/or intimal hyperplasia. The use of living cells and tissues to fabricate a small diameter graft (i.e.

Hemocompatibility of materials used in microelectromechanical systems: platelet adhesion and morphology in vitro.

Microelectromechanical systems (MEMS) create an opportunity for the development of smaller, cheaper, and more precise biomedical instrumentation and devices. Little is known, however, about the hemocompatibility of the materials used to fabricate these devices. Because of the potentially harmful consequences of thrombus formation, a better understanding of blood interactions with bioMEMS materials is desirable.