In vitro antioxidant and enzyme inhibitory properties of Rubus caesius L.

The genus Rubus (Rosaceae) has great potential for and a history of use as natural agents in several traditional folk remedies. Based on this concept, this study focused on the antioxidant activities and enzyme inhibitory effects of extracts and fractions from Rubus caesius. Different chemical assays were performed to detect antioxidant capacity, namely, free radical scavenging (ABTS and DPPH assays), reducing power (CUPRAC and FRAP), phosphomolybdenum and metal chelating.

In Vitro Antiproliferative and Antioxidant Effects of Extracts from Leaves and Their Quality Evaluation.

The present study was performed to evaluate the effect of different extracts and subfractions from leaves on two human colon cancer cell lines obtained from two stages of the disease progression lines HT29 and SW948. Tested samples inhibited the viability of cells, both HT29 and SW948 lines, in a concentration-dependent manner. The most active was the ethyl acetate fraction which, applied at the highest concentration (250 g/mL), decreased the viability of cells (HT29 and SW948) below 66%.