Development of an approach to extracting coronary arteries and detecting stenosis in invasive coronary angiograms.

In stable coronary artery disease (CAD), reduction in mortality and/or myocardial infarction with revascularization over medical therapy has not been reliably achieved. Coronary arteries are usually extracted to perform stenosis detection. As such, developing accurate segmentation of vascular structures and quantification of coronary arterial stenosis in invasive coronary angiograms (ICA) is necessary.

Analyze Informant-Based Questionnaire for The Early Diagnosis of Senile Dementia Using Deep Learning.

Objective: This paper proposes a multiclass deep learning method for the classification of dementia using an informant-based questionnaire.

Methods: A deep neural network classification model based on Keras framework is proposed in this paper. To evaluate the advantages of our proposed method, we compared the performance of our model with industry-standard machine learning approaches.

Effects of aripiprazole on the QTc: a case report.

The use of neuroleptics in the elderly has been a topic of debate since 2005 when the US Food and Drug Administration issued a black-box warning of increased risk of mortality in elderly patients with dementia-related psychosis. Antipsychotic alternatives such as divalproex are sometimes favored on an "off-label" basis to manage agitation in the demented elderly, and antipsychotic use is often clinically necessary to treat psychosis in older adults, with or without dementia. Concurrently, risk for iatrogenic corrected QT (QTc) prolongation on electrocardiogram (ECG) remains a concern with the use of many antipsychotic agents because of its associated potential for fatal arrhythmias.

Pharmacological treatments of non-substance-withdrawal delirium: a systematic review of prospective trials.

Objective: Most reviews of pharmacological strategies for delirium treatment evaluate the effectiveness of these interventions for delirium prevention, reduction in duration and severity of ongoing delirium, and other outcomes that extend beyond the recommendations of expert treatment guidelines. However, little if any attention is given to substantiating the potential benefits of such treatment or addressing the methodological weaknesses that, in part, limit the pharmacological recommendations made by expert treatment guidelines. Therefore, the authors conducted a systematic review to provide the most up-to-date and inclusive review of published prospective trials of potential pharmacological interventions for the prevention and treatment of delirium, and they discuss potential benefits of pharmacological prevention of delirium and/or reduction of ongoing delirium episode duration and severity.

Electroconvulsive therapy (ECT) for catatonia in a patient with schizophrenia and synthetic cannabinoid abuse: a case report.

We present the case of a young man with a long-standing history of schizophrenia who presented with severe and life-threatening catatonia in the setting of synthetic cannabis use who was successfully treated with electroconvulsive therapy. To our knowledge, this is the first reported case of severe and persistent catatonia in the setting of synthetic cannabis use and the first documented successful treatment.

A preliminary investigation of the efficacy of riparian fencing schemes for reducing contributions from eroding channel banks to the siltation of salmonid spawning gravels across the south west UK.

The low productivity of salmonids in many river systems across the UK is testament to their intolerance of water quality perturbations including those associated with excessive sedimentation. Catchment and fishery managers concerned with combating such issues require reliable information on the key sources of the sediment problem to target management and on the efficacy of the mitigation options being implemented. In recognition of the latter requirement, a pre- and post-remediation sediment sourcing survey was used to examine the potential for using sediment tracing to assemble preliminary information on the efficacy of riparian fencing schemes for reducing sediment contributions from eroding channel banks to salmonid spawning gravels in the Rivers Camel, Fal, Lynher, Plym, Tamar and Tavy in the south west of the UK.

Effect of surface material on electrostatic charging of houseflies (Musca domestica L).

Houseflies (Musca domestica L) accumulated electrostatic charges when walking over clean, uncharged dielectric surfaces. The charges elicited on a walking housefly by a range of materials were quantified, allowing a triboelectric series to be determined relative to M domestica. This ranged from surfaces that charged individuals positively, e.