Publications by authors named "Daniel Martinez-Gomez"

Urinary tract infections (UTIs) represent a clinical and epidemiological problem of worldwide impact that affects the economy and the emotional state of the patient. Control of the condition is complicated due to multidrug resistance of pathogens associated with the disease. Considering the difficulty in carrying out effective treatment with antimicrobials, it is necessary to propose alternatives that improve the clinical status of the patients.

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is considered one of the most important zoonotic pathogens worldwide. Highly virulent and antimicrobial-resistant strains of have been reported in recent years, making it essential to understand their ecological origins. In this study, we analyzed the characteristics of strains present in the natural population of American bison () in Mexico.

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Article Synopsis
  • Overuse of antimicrobials has led to the rise of multidrug-resistant bacteria, complicating the treatment of infections like urinary tract infections (UTIs).
  • Autologous bacterial lysates show promise as an alternative treatment for UTIs, but producing individual immunogens can be costly.
  • A study on a polyvalent bacterial lysate containing 10 serotypes demonstrated safety in cell cultures and animals, while effectively stimulating the immune response, suggesting it could help manage chronic UTIs and reduce antimicrobial usage.
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Enterobacteriaceae are considered one the most important zoonotic pathogens. In this study, we analyzed the characteristics of and spp. strains present in carnivores from Janos Biosphere Reserve, Mexico.

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This study was conducted to evaluate the productive performance, intestinal health, and description of the cecum microbiota in broilers supplemented with β-mannanases (MNs) and bacteriophages (BPs). Six hundred one-day-old broilers were divided into four groups and fed one of the following diets: CON-corn-soybean meal + 10 ppm enramycin (ENR); MN: CON + 500 ppm MN; BP: CON + 500 ppm BP; MN + BP: BP + 500 ppm MN. The BP and MN factors showed similar performances to ENR.

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subsp. is the causal agent of sporadic abortion in bovines and infertility that produces economic losses in livestock. In many infectious diseases, the immune response has an important role in limiting the invasion and proliferation of bacterial pathogens.

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Article Synopsis
  • A study evaluated the effects of a polyherbal feed mixture on the growth and health of 40 Holstein calves, examining blood chemistry, biometry, and gene expression during their pre-ruminant to weaning period.
  • The optimal treatment dosage of the polyherbal mixture was found to be 4 g/d, resulting in better weight gain, hip height, and thoracic girth compared to other doses.
  • Gene analysis showed upregulation in processes related to immune response and metabolism, indicating beneficial effects on the calves' health and growth from the herbal treatment.
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Urinary tract infection (UTI) is a relevant public health problem, economically and socially affecting the lives of patients. The increase of antimicrobial bacterial resistance significantly hinders the treatment of UTIs, raising the need to search for alternative therapies. Bacterial lysates (BL) obtained from and other pathogens have been used to treat different infectious diseases with promising results.

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is an important venereal pathogen of cattle that causes infertility and abortions. It is transmitted during mating, and it travels from the vagina to the uterus; therefore, an important cell type that interacts with are endometrial epithelial cells. Several virulence factors have been identified in the genome of , such as adhesins, secretion systems, and antiphagocytic layers, but their expression is unknown.

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Tilmicosin is an antimicrobial agent used to treat intramammary infections against Staphylococcus aureus and has clinical anti-inflammatory effects. However, the mechanism by which it modulates the inflammatory process in the mammary gland is unknown. We evaluated the effect of tilmicosin treatment on the modulation of the mammary innate immune response after S.

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Mastitis in goats is mainly caused by coagulase-negative Staphylococcus (CNS). The identification methods for this group are based on evaluating the expression of phenotypic characteristics such as the ability to metabolize various substrates; however, this is disadvantageous as these methods are dependent on gene expression. In recent years, genotyping methods such as the Multiple Locus Variable-Number Tandem Repeat Analysis (MLVA) and gene identification have been useful for epidemiological study of several bacterial species.

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Amphibians are globally threatened by habitat loss and fragmentation; species within the order Ambystoma are not the exception, as there are 18 species of mole salamanders in México, of which 16 are endemic and all species are under some national or international status of protection. The mole salamander, Ambystoma altamirani is a microendemic species, which is distributed in central México, within the trans-Mexican volcanic belt, and is one of the most threatened species due to habitat destruction and the introduction of exotic species. Nine microsatellite markers were used to determine the genetic structure, genetic variability, effective population size, presence of bottlenecks and inbreeding coefficient of one population of A.

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Background: is one of the major causes of infectious diarrhea worldwide. The distending cytolethal toxin (CDT) of spp. interferes with normal cell cycle progression.

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Human activities are affecting the distribution of species worldwide by causing fragmentation and isolation of populations. Isolation and fragmentation lead to populations with lower genetic variability and an increased chance of inbreeding and genetic drift, which results in a loss of biological fitness over time. Studies of the genetic structure of small and isolated populations are critically important for management and conservation decisions.

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Genealogical records of animals (studbook) are created to avoid reproduction between closely related individuals, which could cause inbreeding, particularly for such endangered species as the Panthera onca (Linnaeus, 1758). Jaguar is the largest felid in the Americas and is considered an important ecological key species. In Mexico, wild jaguar populations have been significantly reduced in recent decades, and population decline typically accompany decreases in genetic variation.

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It is necessary to determine genetic diversity of fragmented populations in highly modified landscapes to understand how populations respond to land-use change. This information will help guide future conservation and management strategies. We conducted a population genetic study on an endemic Mexican Dusky Rattlesnake (Crotalus triseriatus) in a highly modified landscape near the Toluca metropolitan area, in order to provide crucial information for the conservation of this species.

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In the adaptive immune response, the types of cytokines produced define whether there is a cellular (T1) or a humoral (T2) response. Specifically, in the T1 response, interleukin 2 (IL-2), interferon γ (IFN-γ) and tumor necrosis factor β (TNF-β) are produced, whereas in the T2 response, IL-4, IL-5, IL- 6, IL-10 and IL-13 are primarily produced. Cytokines are primarily involved in the regulation of immune system cells.

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