Background: Hepatitis E virus (HEV) is responsible for outbreaks of acute jaundice in Africa and Asia, many of which occur among displaced people or in crisis settings. Although an efficacious vaccine for HEV has been developed, we lack key epidemiologic data needed to understand how best to use the vaccine for hepatitis E control in endemic countries.
Methods: We conducted a systematic review of articles published on hepatitis E in low-income and lower-middle-income countries in Africa and Asia.