Publications by authors named "Daniel Manning"

Article Synopsis
  • This study focuses on creating a new fixed bed bioreactor designed for scalable adherent cell culture, which is vital for advancing cell and gene therapies.
  • The bioreactor features stacked mesh discs for efficient fluid flow and minimal stress on cells, showing excellent uniformity in media distribution during cell growth.
  • The platform is highly effective for automated cell harvesting and maintains a high cell viability rate while allowing for predictable modeling of cell growth, making it a promising tool for large-scale biomanufacturing.
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Purpose: The use of genomics within cancer research and clinical oncology practice has become commonplace. Efforts such as The Cancer Genome Atlas have characterized the cancer genome and suggested a wealth of targets for implementing precision medicine strategies for patients with cancer. The data produced from research studies and clinical care have many potential secondary uses beyond their originally intended purpose.

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