Genotoxicity of dillapiole -butyl ether in mice for the control of .

and are vectors of arboviruses and have different levels of resistance to synthetic insecticides, such as the organophosphate temephos, according to their area of occurrence. As an alternative, there are semisynthetic substances with potential insecticidal effect; however, they need to be fully tested by an effective method for the mosquito control. The semi-synthetic dillapiole butyl ether exhibits toxic ovicidal and larvicidal activity in both mosquito species.

Histopathological, cytotoxicological, and genotoxic effects of the semi-synthetic compound dillapiole -butyl ether in Balb/C mice.

Dillapiole -butyl ether is a substance derived from dillapiole, which exhibits potential insecticidal effects on , the principal vector of the Dengue fever, Zika, and Chikungunya viruses, as well as , a vector of Dengue fever. As these mosquitoes are resistant to synthetic insecticides, dillapiole -butyl ether may represent a valuable, plant-based alternative for their control. Dillapiole -butyl ether has insecticidal and genotoxic effects on and , as shown by the reduction in clutch size and egg viability, and increased mortality rates, as well as a high frequency of micronuclei and chromosomal aberrations.