Publications by authors named "Daniel Lubarsky"
Article Synopsis
- Post-acute sequelae of Coronavirus (PASC), also known as Long COVID, significantly affects endurance athletes, leading to a noticeable decline in their cardiopulmonary health.
- In a study of 45 endurance athletes, those with PASC reported a 27% decrease in cardiopulmonary endurance, while a control group showed no decline; 31% of PASC patients couldn’t do any cardiovascular exercise after 3 months.
- Symptoms like fatigue and shortness of breath were common among PASC subjects, who also exercised less and had worse health scores compared to asymptomatic controls.
Objectives: Neighborhood socioeconomic status, as measured by area deprivation index (ADI) is associated with longer length of stay (LOS) after surgery for hypoplastic left heart syndrome. We tested the hypothesis that LOS is associated with ADI in a large cohort of congenital heart disease (CHD) surgical cases of varying severity and sought to determine which other components of the ADI accounted for any associations.
Design: Retrospective analysis of a curated dataset.
Background: Neonates with apnea of prematurity (AOP) clinically deteriorate because continuous positive airway pressure (CPAP) provides inadequate support during apnea. Neurally adjusted ventilatory assist (NAVA) provides proportional ventilator support from the electrical activity of the diaphragm. When the NAVA level is 0 cmHO/mcV (NAVA-PAP), patients receive CPAP when breathing and backup ventilation when apneic.
View Article and Find Full Text PDFArticle Synopsis
- A pathogenic variant in the UBTF gene, c.628G>A p.Glu210Lys, is linked to a neurodegenerative disorder called Childhood-Onset Neurodegeneration with Brain Atrophy (CONDBA), characterized by early development followed by motor and cognitive regression.
- * The variant results in a change to the UBTF protein that enhances its interaction with DNA, contributing to its gain-of-function activity.
- * A new missense variant, c.608A>G p.(Gln203Arg), also causes significant neurological issues and has a similar mechanism by potentially increasing DNA binding, suggesting it may lead to a different phenotype associated with UBTF dysfunction.