Relationship between muscle strength parameters and functional capacity in persons with mild to moderate degree multiple sclerosis.

Background: Maximal muscle strength has been shown to be an important predictor of functional capacity for persons with multiple sclerosis (PwMS). Another muscle strength parameter known to be important for functional capacity in other patient groups is rate of force development (RFD) in knee extensors and flexors. This has not been investigated for PwMS.

Validity and reliability of VO₂-max measurements in persons with multiple sclerosis.

Background: Direct measurement of whole body maximal oxygen consumption (VO2-max test) is considered the gold standard when assessing cardiorespiratory fitness. Nonetheless, the validity and reliability of the test have not been examined in persons with multiple sclerosis (PwMS).

Objective: To investigate the validity and reliability of VO2-max measurements in PwMS, and additionally to compare these measures to those of healthy controls.