Background: Asthma is the most common chronic disease in children, resulting in considerable morbidity and healthcare utilisation, especially in geographical areas with high deprivation. Parents play a pivotal role in children's asthma management.
Aim: To explore the views of parents whose children have asthma, regarding barriers and facilitators to receiving adequate asthma care.
Highly charged ions (HCIs) offer many opportunities for next-generation clock research due to the vast landscape of available electronic transitions in different charge states. The development of extreme ultraviolet frequency combs has enabled the search for clock transitions based on shorter wavelengths in HCIs. However, without initial knowledge of the energy of the clock states, these narrow transitions are difficult to be probed by lasers.
View Article and Find Full Text PDFThe absolute atomic mass of Pb has been determined with a fractional uncertainty of by measuring the cyclotron-frequency ratio of Pb to Xe with the high-precision Penning-trap mass spectrometer Pentatrap and computing the binding energies and of the missing 41 and 26 atomic electrons, respectively, with the fully relativistic multi-configuration Dirac-Hartree-Fock (MCDHF) method. has been measured with a relative precision of . and have been computed with an uncertainty of 9.
View Article and Find Full Text PDFIn this paper, we report on the development of a fast high-voltage switch, which is based on two enhancement mode N-channel silicon carbide metal-oxide-semiconductor field-effect transistors in push-pull configuration. The switch is capable of switching high voltages up to 600 V on capacitive loads with rise and fall times on the order of 10 ns and pulse widths ≥20 ns. Using this switch, it was demonstrated that, from the charge state distribution of bunches of highly charged ions ejected from an electron beam ion trap with a specific kinetic energy, single charge states can be separated by fast switching of the high voltage applied to a Bradbury-Nielsen Gate with a resolving power of about 100.
View Article and Find Full Text PDFThe possibility of applying active feedback to a single ion in a Penning trap using a fully digital system is demonstrated. Previously realized feedback systems rely on analog circuits that are susceptible to environmental fluctuations and long term drifts, as well as being limited to the specific task they were designed for. The presented system is implemented using a field-programmable gate array (FPGA)-based platform (STEMlab), offering greater flexibility, higher temporal stability, and the possibility for highly dynamic variation of feedback parameters.
View Article and Find Full Text PDFA diastereoselective Co(CO)-mediated Pauson-Khand reaction (PKR) of siloxy-tethered 1,7-enynes for the synthesis of cyclopentaoxasilinones has been developed. This transformation can be performed on a multigram scale and is characterized by a broad substrate scope, functional group compatibility, and high chemo- and diastereoselectivity. Oxidation of the resulting cyclopentaoxasilinones delivers stereoenriched β-alkylated cyclopentenones, which are inaccessible by intermolecular PKRs.
View Article and Find Full Text PDFRenal function of potential living kidney donors is routinely assessed with scintigraphy. Kidney anatomy is evaluated by imaging techniques such as magnetic resonance imaging (MRI). We evaluated if a MRI-based renal volumetry is a good predictor of kidney function pre- and postdonation.
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