Publications by authors named "Daniel Karpel"
Article Synopsis
- * A case report discusses a 25-year-old woman with viral myocarditis, illustrating the challenges of diagnosing the condition due to its varied symptoms.
- * After comprehensive diagnostic tests and treatment with diuretics, antibiotics, and medical therapy, her health improved, underscoring the importance of early detection and intervention to prevent long-term complications.
Article Synopsis
- Clopidogrel is a crucial medication used to prevent complications like restenosis and cardiovascular events after stent placement, but its effectiveness relies on the patient's genetic makeup, specifically CYP2C19 alleles.
- Genetic variations can lead to poor responses to clopidogrel in about 30% of patients, highlighting the need to understand global variations in these genetic markers.
- The study advocates for pre-treatment genotyping to tailor medications to individuals, ensuring better outcomes and reducing risks in patients with genetic variants affecting drug metabolism.
Background Previous studies have shown that patients with heart failure (HF) and cardiogenic shock (CS) have worse outcomes when admitted over the weekend. Since peripartum cardiomyopathy (PPCM) is a cause of CS and persisting HF, it is reasonable to extrapolate that admission over the weekend would also have deleterious effects on PPCM outcomes. However, the impact of weekend admission has not been specifically evaluated in patients with PPCM.
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