Creation of a drug-coated glaucoma drainage device using polymer technology: in vitro and in vivo studies.

Objective: To create and test a slow-release antifibrotic drug-coated glaucoma drainage device using in vitro and in vivo experiments.

Methods: A slow-release device incorporating mitomycin C in poly(2-hydroxyethyl methacrylate) disks was developed using redox-polymerization techniques. A standardized preparation of this drug delivery device was attached to the Ahmed glaucoma valve (model FP7; New World Medical, Inc, Rancho Cucamonga, California).