C3-Dominant Infection Related Crescentic Glomerulonephritis.

Infection related glomerulonephritis and more specifically streptococcal glomerulonephritis is a rare disease in adults, and so is C3 glomerulonephritis. It has been recognized that a clinical and morphological overlap between these two entities exists. We present a case of a 59-year-old man with previous treated HIV infection with virological response, treated hepatitis b infection, treated syphilis and non-Hodgkin lymphoma in remission; presenting and acute sore throat with high ASO titers two weeks before a rapidly progressive glomerulonephritis requiring dialysis since presentation; biopsy showed acute diffuse and proliferative glomerulonephritis with crescentic pattern with exclusive C3 staining.