Publications by authors named "Daniel Heffernan-Ho"

Sarcoidosis is an idiopathic inflammatory systemic disorder that is believed to be caused by a mixture of environmental factors and genetic predisposition. Less than 50 cases of testicular sarcoidosis have been presented in the literature over the last two decades, making it an extremely rare form of the disease. Furthermore, the radiological pathognomonic features are less well documented.

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Background And Objective: The majority of small testicular masses (STMs) are benign and therefore radical orchidectomy (RO) may represent overtreatment. In appropriately selected patients, surveillance or testis-sparing surgery (TSS) is an alternative option to preserve testicular function. Since there are no clear guidelines, we aimed to develop consensus recommendations on the management of STMs.

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Article Synopsis
  • The study explored the effectiveness of using semi-automated software for second reads of prostate MRI scans in one-stop clinics, assessing if this method could lead to fewer biopsy procedures.
  • Out of 664 patients, 31% had equivocal scan results (scored Likert 3), with 61% showing agreement between first and second readings, and 30% of biopsies revealing significant disease.
  • Using the new workflow, nearly 24% of biopsies for equivocal scans could have been avoided, highlighting the method's potential to reduce unnecessary procedures and related side effects.
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Background: Robotic radical prostatectomy (RARP) is a first-line curative treatment option for localized prostate cancer. Postoperative erectile dysfunction and urinary incontinence are common associated adverse side effects that can negatively impact patients' quality of life. Preserving the lateral neurovascular bundles (NS) during RARP improves functional outcomes.

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The accuracy of multi-parametric MRI (mpMRI) in the pre-operative staging of prostate cancer (PCa) remains controversial. The purpose of this study was to evaluate the ability of mpMRI to accurately predict PCa extra-prostatic extension (EPE) on a side-specific basis using a risk-stratified 5-point Likert scale. This study also aimed to assess the influence of mpMRI scan quality on diagnostic accuracy.

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Background: Two million non-emergency surgeries are being cancelled globally every week due to the COVID-19 pandemic, which will have a major impact on patients and healthcare systems.

Methods: During the peak of the pandemic in the United Kingdom, we set up a multicentre cancer network amongst 14 National Health Service institutions, performing urological, thoracic, gynaecological and general surgical urgent and cancer operations at a central COVID-19 cold site. This is a cohort study of 500 consecutive patients undergoing surgery in this network.

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Objectives: To report on the methods, peri-operative outcomes and histopathological concordance between frozen and final section from the NeuroSAFE PROOF feasibility study (NCT03317990).

Patients And Methods: Between May 2018 and March 2019, 49 patients at two UK centres underwent robot-assisted radical prostatectomy (RARP). Twenty-five patient were randomized to NeuroSAFE RARP (intervention arm) and 24 to standard RARP (control arm).

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Introduction: Glans hypermobility presents a rarely observed complication of penile prosthesis implantation. It may result in patient dissatisfaction because of painful intercourse, difficulties during penetrative sex, and a poor cosmetic result. This problem may prevent the patient from using an otherwise fully functional implant.

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The aims of our study were to describe our case series of three urethral diverticulum carcinomas (UDC) in women and to review the literature on UDC in females to determine patient characteristics, presenting symptoms and outcomes along with optimal investigations and treatment modalities. A literature search was performed utilizing Medline, EMBASE and the Cochrane library for all papers including case reports on UDC in women published to date. The results along with those of our three cases are detailed.

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