Publications by authors named "Daniel Guillen Pinto"

Article Synopsis
  • Tuberculosis, and specifically central nervous system tuberculosis (CNS-TB), is a major global health issue, making up 1-10% of all TB cases, particularly affecting children.
  • The article highlights key CNS-TB forms in children, such as tuberculous meningitis and tuberculomas, along with potential complications that may arise.
  • It stresses the significance of diagnostic imaging techniques like CT and MRI for early detection and emphasizes the need for increased awareness among healthcare professionals to ensure timely treatment and better outcomes for affected children.
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  • A nine-month-old boy presented with fever, irritability, and seizures, leading to a diagnosis of febrile focal status epilepticus after three days of symptoms.
  • A lumbar puncture revealed inflammation in the cerebrospinal fluid, but tests for several pathogens were negative, while tests confirmed a COVID-19 infection.
  • An MRI indicated acute necrotizing encephalopathy, and despite mechanical ventilation, the child's condition worsened, marking this as the first pediatric case linked to SARS-CoV-2.
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  • This study investigated how reading augmented reality (AR) books affects salivary cortisol levels in hospitalized kids aged 7-11, comparing it to reading traditional children's books.
  • The trial involved 29 children and found that while cortisol levels decreased after reading AR books, the reduction was not significantly greater than that seen after reading standard books. VAS scores for psychological stress increased after the AR intervention.
  • Findings suggest the need for more research, as the initial results showed no advantage of AR books over standard ones in lowering cortisol levels, though there was a noted increase in psychological stress scores with AR.*
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Objectives: To assess the risk of brain damage in premature infants under 34 weeks of gestational age exposed to histological chorioamnionitis (HCA).

Materials And Methods: A cohort study was conducted at the Hospital Cayetano Heredia, during 2015. Premature infants under 34 weeks of gestational age, who had histopathological examination of the placenta, were included.

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Objective: To determine the incidence and the clinical, bacteriological and cerebrospinal fluid characteristics of neonatal meningitis in Lima hospitals.

Materials And Methods: An observational, multicenter study was conducted in six hospitals in the city of Lima during 1 year of epidemiological surveillance.

Results: The cumulative hospital incidence was 1.

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We report the case of an infant born with congenital Zika syndrome (CZS). During the largest Zika virus (ZIKV) outbreak in Peru, the mother presented with fever and rash that were confirmed to be due to ZIKV by real-time PCR. The infant was born with severe microcephaly.

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Article Synopsis
  • Scientists studied 385 babies in Lima, Peru, who weighed less than 2,000 grams at birth between May 2012 and July 2014.
  • They found that 19.2% of babies under 1,500 grams had a brain bleed called intraventricular hemorrhage, and 9.6% had a severe type of this bleed.
  • The study showed that babies with this condition had a high risk of death (47.1%), and another issue called periventricular leukomalacia was found in 5.4% of the babies, especially among those with lower birth weight.
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Objectives.: To determine the ratio of microcephaly in newborns in level II and III health facilities of the Ministry of Health (MINSA) of Peru for the period 2005-2013.

Materials And Methods.

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Objective: To evaluate the combined prognostic value of neurological examination, head circumference and cranial ultrasound for neurodevelopmental delay (NDD) in very low birth weight (VLBW, <1500 g) preterm infants.

Methods: Prospective follow-up study. Preterm infants with VLWB were assessed for NDD using the Mullen Scales of Early Learning test at 24 months of corrected age.

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Non-epileptic paroxysmal disorders are frequent events in the neonate, generally transient. However, due to their intensity they can be confused as true epileptic seizures. The objective of this review is to update the concepts in relation to tremors, neonatal benign sleep myoclonus (MNBS) and hyperekplexia.

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Aiming at describing the incidence, clinical characteristics and factors associated with neonatal meningitis (NM), a case series study was conducted from 2008 to 2015, where 53 neonates, 10 with early onset NM and 43 with late onset were included. An incidence of 1.5 per thousand live births and a lethality of 3.

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  • The study aimed to assess the clinical features and outcomes of pneumococcal meningitis in children under 16 in Lima, Peru, analyzing cases from 2006 to 2011.
  • Out of 44 cases, a significant 68.2% involved children under 2 years old, with a high fatality rate of 32.6%, mostly within the first two days; malnutrition also correlated with fatalities.
  • Over 40% of pneumococcal strains showed resistance to penicillin, with common serotypes being 6B, 14, 19F, and 23F, emphasizing the need for prompt diagnosis and effective vaccination.
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The objective of this study was to analyze the use of lumbar punctures (LP) in the evaluation of late-onset neonatal sepsis. It is recommended to perform an LP as part of the evaluation of late-onset sepsis. We used a cohort of 414 newborns with a birth weight <2000g in three hospitals in Lima.

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In order to describe the characteristics of traumatic brain injury (TEC) in children seen at the Cayetano Heredia National Hospital from 2004 to 2011, a case study was conducted. 316, 14 year-old minors were included, the median age was 4 ± 3 years old. 63.

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The aim of this study was to describe the concentration of lead in umbilical cord blood (UCB) of neonates born from primiparous women who live in northern Lima. A cross sectional study was carried out at Cayetano Heredia National Hospital, from July 2011 to January 2012. 100 neonates born from primiparous women who lived in northern Lima in the previous 5 years or more were included.

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