Vitiligo and Crohn's disease form an autoimmune cluster: insights from a population-based study.

Background: While the coexistence of vitiligo and Crohn's disease (CD) has been reported in individual patients, the epidemiological association between these autoimmune conditions remains inconclusive.

Objective: To assess the bidirectional association between vitiligo and CD.

Methods: A population-based study was performed to compare vitiligo patients ( = 20,851) with age-, sex- and ethnicity-matched control subjects ( = 102,475) regarding the incidence of new-onset and the prevalence of preexisting CD.