Clin Spine Surg
February 2024
Study Design: Narrative review.
Objective: To provide an overview of the evaluation and diagnosis of degenerative cervical myelopathy (DCM).
Summary Of Background Data: DCM describes several etiologies of degenerative, nontraumatic spinal cord impairment.
Spexin (SPX) and galanin (GAL) are two neuropeptides widely expressed in the central nervous system as well as within peripheral tissues in humans and other species. SPX and GAL mediate their biological actions through binding and activation of galanin receptors (GALR), namely GALR1, GALR2 and GLAR3. GAL appears to trigger all three galanin receptors, whereas SPX interacts more specifically with GALR2 and GLAR3.
View Article and Find Full Text PDFIntroduction: Perilunate dislocations and perilunate fracture-dislocations (PLFD) are relatively uncommon injuries, comprising <10% of wrist injuries. Perilunate injuries are often complicated by median neuropathy reported in 23-45% of cases, whereas there are very few reported cases of associated ulnar neuropathy. Combined greater arc and inferior arc injuries are also rare.
View Article and Find Full Text PDFThis systematic review investigates the emissions from ultrasonic humidifiers (e.g., cool mist humidifiers) within indoor air environments, namely soluble and insoluble metals and minerals as well as microorganisms and one organic chemical biocide.
View Article and Find Full Text PDFThe commonly used consumer product of an ultrasonic humidifier (e.g., cool mist humidifier) emits fine particles containing metals from tap water used to fill the humidifier.
View Article and Find Full Text PDFElectronic health records (EHRs) have provided physicians with a systematic framework for collecting patient data, organizing notes from the healthcare team, and managing the daily workflow in the modern era of healthcare. Despite these advantages, EHRs have proven to be problematic for clinicians. The burdensome regulations requiring increased documentation with the EHR paradigm have led to inefficiencies from data-entry requirements forcing physicians to spend an inordinate amount of time on it, affecting the time available for direct patient care as well as leading to professional burnout.
View Article and Find Full Text PDFPreterm birth affects more than 10% of all births worldwide. Such infants are much more prone to Growth Faltering (GF), an issue that has been unsolved despite the implementation of numerous interventions aimed at optimizing preterm infant nutrition. To improve the ability for early prediction of GF risk for preterm infants we collected a comprehensive, large, and unique clinical and microbiome dataset from 3 different sites in the US and the UK.
View Article and Find Full Text PDFA complex dataset with 140 sampling events was generated using triple quadrupole gas chromatography-mass spectrometer to track the occurrence of 95 odorants in raw and finished water from 98 drinking water treatment plants in 31 cities across China. Data analysis identified more than 70 odorants with concentrations ranging from not detected to thousands of ng/L. In raw water, Pearson correlation analysis determined that thioethers, non-oxygen benzene-containing compounds, and pyrazines were classes of chemicals that co-occurred, and geosmin and ()-cresol, as well as cyclohexanone and benzaldehyde, also co-occurred, indicating similar natural or industrial sources.
View Article and Find Full Text PDFUnlabelled: The essential trace element manganese (Mn) can cause neurotoxicity with inhalation acknowledged as a more severe health and cognition threat than ingestion.
Methods: Over a range of aqueous Mn concentrations present in tap water, this research characterizes exposures and risks for adults and 0.25, 1, 2.
Room-sized ultrasonic humidifiers are exposure pathways to aerosolized metals, with dose positively associated with increased concentrations of metals in fill water. This study innovatively quantifies water ingestion along with inhalation doses from humidifiers for 10-1000 μg/L dissolved lead (Pb) in tap water. The subsequent indoor air Pb concentrations, average daily doses, and inhalation deposited respiratory fractions were predicted under four room scenarios for 3-mo, 12-mo, 28-mo, and 6-yr children and adults.
View Article and Find Full Text PDFSalmonella, Shiga toxin-producing Escherichia coli (STEC), and Listeria monocytogenes have been isolated from low water activity foods (LWAF), where they may survive for extended periods. The ready-to-eat nature of many LWAF, such as dried fruits and nuts, warrants effective post-harvest thermal treatment for the reduction of pathogens such as low-temperature, saturated steam, also known as vacuum-assisted steam pasteurization. The objective of this study was to determine reductions of Salmonella, STEC, L.
View Article and Find Full Text PDFDrinking water supplied by private wells is a national concern that would benefit from improved outreach and support to ensure safe drinking water quality. In North Carolina (NC), local health departments (LHDs) have private well programs that enforce statewide well construction standards, offer water testing services, and provide well water outreach and assistance. Programs were evaluated to determine their capacity and capability for well water outreach and assistance and identify differences among programs.
View Article and Find Full Text PDFFine particulates and aerosols emitted by commonly used, room-sized ultrasonic humidifiers may pose adverse health effects to children and adults. The literature documents adverse effects for children exposed to minerals emitted from humidifiers. This study performs novel and comprehensive characterization of bivariate particle size and element concentrations of emitted airborne aerosols and particles from ultrasonic humidifiers filled with tap water, including size distribution from 0.
View Article and Find Full Text PDFUltrasonic humidifiers provide indoor relief to symptoms caused by dry air and produce aerosols containing both water and minerals that are present in the water that fills the humidifier. This study investigated the spatial distributions, concentrations, and metal and mineral composition of aerosols emitted when an ultrasonic humidifier was filled with deionized water (DI), low mineral tap water (LL), high total dissolved solids (TDS)/high hardness water (HH), and high TDS/low hardness water (HL). Aerosol/particle sizes and counts were obtained at six horizontal distances in both the plume and near floor for each water quality.
View Article and Find Full Text PDFThe presence of earthy-musty odors in drinking water is a major concern for water suppliers and consumers worldwide. While geosmin and 2-methylisoborneol are the most studied earthy-musty odor-causing compounds, pyrazine and its alkyl and methoxy compounds possess similar odors and are widely distributed in nature, foods, and beverages. In this study, odor characteristics of pyrazines and their presence in natural and treated waters were determined.
View Article and Find Full Text PDFTo characterize human emotions, researchers have increasingly utilized Automatic Facial Expression Analysis (AFEA), which automates the Facial Action Coding System (FACS) and translates the facial muscular positioning into the basic universal emotions. There is broad interest in the application of FACS for assessing consumer expressions as an indication of emotions to consumer product-stimuli. However, the translation of FACS to characterization of emotions is elusive in the literature.
View Article and Find Full Text PDFFront Psychol
December 2019
In this mini-review, I use event-related potential (ERP) studies to test the minimalist program (MP) prediction that organisms with the faculty of language cognitively process languagelike systems in a qualitatively distinct manner. I first discuss "languagelike" as a technical term defined by recursion criteria. From this definition and using a generative perspective, I show that certain domains of math and music can be considered languagelike.
View Article and Find Full Text PDFUltrasonic humidifier use is a potential source of human exposure to inhalable particulates. This research evaluated the behavior of insoluble iron oxide and aluminum oxide particles in water used to fill room-sized ultrasonic humidifiers. Solutions of 10 mg/L Fe, as iron oxide particles, or 5 mg/L Al, as aluminum oxide suspension, were added into tap water used to fill ultrasonic humidifiers.
View Article and Find Full Text PDFVarious antimicrobial interventions are applied sequentially in the beef processing industry to reduce microbial load on beef products by using intensive inputs (e.g., chemicals, energy), high strength wastewater, and potentially result in meat discoloration.
View Article and Find Full Text PDFEnviron Sci Process Impacts
January 2019
Benzene, toluene, ethylbenzene, and xylenes (BTEX) are hazardous air pollutants commonly found in outdoor air. Several studies have explored the potential of vegetation to mitigate BTEX in outdoor air, but they are limited to a northern temperate climate and their results lack consensus. To investigate this subject in a subtropical climate, we deployed passive air samplers for two weeks in parks and outside nearby residences at four locations: three in an urban area and one in a rural area in Alabama, USA.
View Article and Find Full Text PDFInfectious diseases caused by enveloped viruses, such as influenza, severe acute respiratory syndrome (SARS), and Middle East respiratory syndrome (MERS), cause thousands of deaths and billions of dollars of economic losses per year. Studies have found a relationship among temperature, humidity, and influenza virus incidence, transmission, or survival; however, there are contradictory claims about whether absolute humidity (AH) or relative humidity (RH) is most important in mediating virus infectivity. Using the enveloped bacteriophage Phi6, which has been suggested as a surrogate for influenza viruses and coronaviruses, we designed a study to discern whether AH, RH, or temperature is a better predictor of virus survival in droplets.
View Article and Find Full Text PDFListeria monocytogenes (L. monocytogenes) causes the third highest number of foodborne illness deaths annually. L.
View Article and Find Full Text PDFCattle coming from feedlots to slaughter often harbor pathogenic E. coli that can contaminate final meat products. As a result, reducing pathogenic contamination during processing is a main priority.
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