Anticancer Activity of Nonpolar Pt(CH)I{} is Found to be Superior among Four Similar Organoplatinum(IV) Complexes.

The anticancer properties of well-defined molecules serve to bolster the field of metals in medicine. Such compounds, particularly those of platinum and their closely related structural analogs, continue to be potentially highly interesting to researchers and clinicians alike. The four octahedral organoplatinum(IV) compounds [Pt(CH)X{ }] (X = Br, I; = 2,2'-bipyridine, 2,2'-bipyridine-4,4'-dicarboxylic acid) have been isolated and structurally characterized by single-crystal X-ray diffraction.

Growth factors in plastic surgery.

Recent advances in molecular biology and tissue engineering [9] have provided useful tools for improving surgery in general and plastic surgery in particular [11]. Advancing knowledge of cell function and easier ways to obtain active substances or even cells with specific activity have led to more frequent use of many surgical procedures. The active substances that participate in the restoration of damaged tissues are known as growth factors (fundamentally contained in platelets), cytokines, chemokines [16], and similar factors such as interleukins and tissue necrosis factors.