Synopsis of recent research by authors named "Daniel F Wyss"
- Recent research by Daniel F Wyss focuses on the mechanistic understanding of the RIG-I protein in immune response activation, revealing insights into its structural dynamics and activation mechanisms that distinguish viral from endogenous RNA.
- Wyss's work also includes the development of new therapeutic strategies, such as novel cyclic dinucleotide STING agonists with potential applications in cancer treatment and the discovery of inhibitors against metallo-beta-lactamases to combat bacterial infections.
- Additionally, his contributions to fragment-based drug discovery methodologies enhance the identification of potent enzyme inhibitors, leveraging NMR and crystallographic techniques to optimize lead compounds for various health applications.
