Publications by authors named "Daniel Eurien"
Introduction: isoniazid preventive therapy (IPT) is highly effective at preventing tuberculosis among Persons Living with HIV (PLHIV). However, IPT completion rates in Uganda have not been studied. We examined completion rates for the 6-month course of IPT and factors associated with non-completion among PLHIV in northeastern Uganda.
View Article and Find Full Text PDFBackground: Uganda has had seven Ebola disease outbreaks, between 2000 and 2022. On Sept 20, 2022, the Ministry of Health declared a Sudan virus disease outbreak in Mubende District, Central Uganda. We describe the epidemiological characteristics and transmission dynamics.
View Article and Find Full Text PDFBackground: On 20 September 2022, Uganda declared its fifth Sudan virus disease (SVD) outbreak, culminating in 142 confirmed and 22 probable cases. The reproductive rate (R) of this outbreak was 1.25.
View Article and Find Full Text PDFOn 20th September 2022, Uganda declared the 7th outbreak of Ebola virus disease (EVD) caused by the Sudan Ebola strain following the confirmation of a case admitted at Mubende Regional Referral Hospital. Upon confirmation, the Government of Uganda immediately activated the national incident management system to initiate response activities. Additionally, a multi-country emergency stakeholder meeting was held in Kampala; convening Ministers of Health from neighbouring Member States to undertake cross-border preparedness and response actions.
View Article and Find Full Text PDFArticle Synopsis
- Communicable diseases, particularly tuberculosis (TB) and HIV/AIDS, are major health issues in refugee settings, contributing significantly to morbidity and mortality during complex emergencies.
- A study was conducted on TB treatment outcomes among 254 patients at two healthcare facilities in Kyangwali Refugee Settlement, revealing that 55% of patients had favorable outcomes while 45% had unfavorable ones.
- Factors such as increasing age were linked to unfavorable outcomes, and those diagnosed with multidrug-resistant TB (MDR-TB) had better odds of achieving favorable treatment outcomes, although overall treatment success rates were lower than the World Health Organization's recommended 85%.
Article Synopsis
- The COVID-19 pandemic spread across borders and prompted countries like the Democratic Republic of the Congo, Tanzania, and Uganda to analyze population movement for better disease response starting May 2020.
- Health ministries conducted focus groups and participatory mapping to identify key areas for COVID-19 surveillance, outreach, and collaboration across borders.
- Despite different approaches, all three countries adapted their health strategies during the pandemic, showcasing how governments tailor their responses based on local cultural and cross-border needs to enhance global health security.
Despite remarkable progress in controlling HIV and TB, Uganda is one of the 30 high-burden TB/HIV countries. Approximately 53,000 Ugandans had a new HIV diagnosis in 2019, and approximately 88,000 Ugandans had a TB diagnosis in 2020. Fellows in the Uganda Public Health Fellowship Program (UPHFP) work directly with the Ministry of Health AIDS and TB Control Programs, the U.
View Article and Find Full Text PDFArticle Synopsis
- Jimsonweed (Datura stramonium) is a toxic plant that can cause severe gastrointestinal and neurological symptoms, leading to potential fatalities; an outbreak occurred in March 2019, affecting over 200 individuals in specific districts.
- The investigation defined suspected cases based on specific symptoms and involved a detailed retrospective cohort study to analyze dietary habits and food exposure, alongside extensive laboratory testing of food samples.
- A total of 293 suspected cases were identified, with a significant link to a batch of fortified corn-soy blend (CSB+) consumed during the outbreak, which was found to contain toxic alkaloids linked to the symptoms experienced by the patients.
Background: Kampala city slums, with one million dwellers living in poor sanitary conditions, frequently experience cholera outbreaks. On 6 January 2019, Rubaga Division notified the Uganda Ministry of Health of a suspected cholera outbreak in Sembule village. We investigated to identify the source and mode of transmission, and recommended evidence-based interventions.
View Article and Find Full Text PDFBackground: On 18 January 2018 a 40 year old man presented with skin lesions at Rhino Camp Health Centre. A skin lesion swab was collected on 20 January 2018 and was confirmed by PCR at Uganda Virus Research Institute on 21 January 2018. Subsequently, about 9 persons were reported to have fallen ill after reporting contact with livestock that died suddenly.
View Article and Find Full Text PDFArticle Synopsis
- Crimean-Congo haemorrhagic fever (CCHF) is a viral disease transmitted by ticks, causing severe hemorrhagic symptoms, with multiple outbreaks reported in Uganda, primarily in the 'cattle corridor'.
- A study conducted from July 2018 to January 2019 identified 14 confirmed cases, all with fever and a high prevalence of unexplained bleeding, resulting in a significant case-fatality rate of 36%.
- Risk factors included close contact with livestock, living near grazing fields, and a high incidence of tick attachment, highlighting the need for targeted interventions to prevent future outbreaks.
Article Synopsis
- - The Uganda Ministry of Health announced a cholera outbreak in the Kyangwali Refugee Settlement on February 23, 2018, with over 60 individuals affected, leading to an investigative study to assess the outbreak's extent and transmission methods.
- - Investigators defined cholera cases based on symptoms and conducted a case-control study, finding a case-fatality rate of 2.1% with the highest impact on individuals from the Democratic Republic of Congo.
- - The outbreak lasted four months and was linked to contaminated stream water resulting from open defecation, with an overall attack rate of 3.2 per 1000 people in Hoima District.
A study of patient records in four HIV clinics in three sub-Saharan African countries examined routine clinical care patterns and variations. Clinic characteristics were described, and patient data extracted from a sample of medical records. Data on treatment, CD4 count and viral load (VL) were obtained for the last visit in the records, dates mainly between 2015 and 2017, patient demographic data were obtained from the first clinic visit.
View Article and Find Full Text PDF