Publications by authors named "Daniel Edon"
Circulating protein biomarkers have demonstrated utility as a diagnostic tool in predicting musculoskeletal disease severity, but their utility in the evaluation of shoulder lesions associated with shoulder instability is unknown. Thus, the purpose of this exploratory study was to determine whether preoperative biomarkers of cartilage turnover and inflammation are associated with specific shoulder lesions in shoulder instability. Thirty-three patients (29.
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- COVID-19, caused by the SARS-CoV-2 virus, is a pandemic that primarily affects the respiratory system, though it can have severe implications for other organ systems, including musculoskeletal health.
- While many infected individuals show mild or no symptoms, some experience long-lasting effects on their quality of life, similar to issues seen in the past with the related SARS-CoV-1 virus.
- This article aims to summarize existing musculoskeletal problems linked to both SARS and COVID-19, while leveraging computational models and biochemical studies to predict potential long-term impacts of SARS-CoV-2 infection on musculoskeletal cells.
The Use of Recombinant Human Growth Hormone to Protect Against Muscle Weakness in Patients Undergoing Anterior Cruciate Ligament Reconstruction: A Pilot, Randomized Placebo-Controlled Trial.
Christopher L Mendias Elizabeth R Sibilsky Enselman Adam M Olszewski Jonathan P Gumucio Daniel L Edon
Am J Sports Med
July 2020
Article Synopsis
- ACL tears are common injuries that often leave patients with persistent quadriceps weakness post-reconstruction, increasing the risk of knee osteoarthritis even after extensive rehabilitation.
- A study hypothesized that a 6-week treatment with human growth hormone (HGH) would protect against muscle atrophy and weakness during the ACL recovery process compared to placebo.
- In a trial with 19 male participants, HGH showed significant improvements in knee extension strength and a notable increase in a biomarker for muscle growth, suggesting potential benefits of HGH treatment after ACL surgery.