Publications by authors named "Daniel Dobrin"
Background: Traditional hookah smoking has grown quickly to become a global tobacco epidemic. More recently, electronic hookahs (e-hookahs)-vaped through traditional water pipes-were introduced as healthier alternatives to combustible hookah. With combustible tobacco smoking, oxidative stress, inflammation, and vascular stiffness are key components in the development and progression of atherosclerosis.
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- E-hookah vaping is popular among youth, but it produces harmful aerosols containing nicotine and oxidants that can damage blood vessels and reduce nitric oxide function.
- A study on young adult habitual hookah smokers showed that a 30-minute e-hookah session significantly decreased endothelial function, measured by reduced brachial artery flow-mediated dilation (FMD), and increased plasma nicotine levels.
- Infusing the antioxidant ascorbic acid improved FMD and counteracted the negative effects of e-hookah vaping, suggesting that oxidative stress plays a critical role in the vascular impairment associated with vaping.