Publications by authors named "Daniel Demehin"
Detecting early cancer through liquid biopsy is challenging due to the lack of specific biomarkers for early lesions and potentially low levels of these markers. The current study systematically develops an extracellular-vesicle (EV)-based test for early detection, specifically focusing on high-grade serous ovarian carcinoma (HGSOC). The marker selection is based on emerging insights into HGSOC pathogenesis, notably that it arises from precursor lesions within the fallopian tube.
View Article and Find Full Text PDFArticle Synopsis
- Ovarian cancer is a complex disease with different types, but high-grade serous carcinoma (HGSOC) is the most common and often diagnosed late, making it harder to treat.
- Researchers are creating a new blood test that can detect early-stage HGSOC using tiny particles released by cells, called extracellular vesicles (EVs).
- In tests, this new method showed it could accurately identify early cancer, which is important for better treatment options for women at risk of ovarian cancer.