Publications by authors named "Daniel De Luis-Roman"

Background and aims: omentin-1 might present a potential role in metabolic syndrome (MS). The aim of our investigation was to evaluate the relationship between omentin-1 and nascent MS. Methods: we carried out a cross-sectional study in 606 obese subjects.

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  • User-friendly assessment tools for malnutrition are essential, and this study focused on a personalized nutrition intervention using a new oral nutritional supplement and AI technology to track outcomes in malnourished patients.
  • The study included 65 patients and showed significant improvements over three months, with weight loss decreasing, and a drop in the prevalence of malnutrition and severe malnutrition.
  • Additionally, older patients experienced gains in muscle thickness, strength, and function, indicating that tailored interventions can effectively enhance nutrition and combat malnutrition in patients with disease-related issues.
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  • The weight-adjusted waist index (WWI) was evaluated for its ability to predict metabolic syndrome (MS) specifically among Caucasian individuals with obesity.
  • A study involving 2,162 obese Caucasian patients found that those in the highest WWI category were significantly more likely to have MS, with adjusted odds ratios demonstrating a clear trend linked to higher WWI levels.
  • Results indicated that the WWI has good predictive accuracy for MS with a cut-off value of 11.59, showing a sensitivity of 70% and specificity of 93.4%.
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Objectives: The aim of this investigation was to evaluate the discrepancies between bioelectrical impedance analysis (BIA) and computed tomography (CT) in assessing skeletal muscle mass and identifying low muscle mass in patients with colorectal cancer.

Methods: This study recruited 137 patients with colorectal cancer from February 2028 to December 2023. CT scans were analyzed at the Lumbar 3 vertebral level to determine the area of skeletal muscle, which was then utilized to estimate whole-body skeletal muscle mass.

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Background: A nationwide, prospective, multicenter, cohort study (the Disease-Related caloric-protein malnutrition EChOgraphy (DRECO) study) was designed to assess the usefulness of ultrasound of the rectus femoris for detecting sarcopenia in hospitalized patients at risk of malnutrition and to define cut-off values of ultrasound measures.

Methods: Patients at risk of malnutrition according to the Malnutrition Universal Screening Tool (MUST) underwent handgrip dynamometry, bioelectrical impedance analysis (BIA), a Timed Up and Go (TUG) test, and rectus femoris ultrasound studies. European Working Group on Sarcopenia in Older People (EWGSOP2) criteria were used to define categories of sarcopenia (at risk, probable, confirmed, severe).

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  • The study assessed the effects of a diabetes-specific enteral nutrition formula on glycemia, comorbidities, and mortality in non-diabetic acute stroke patients requiring feeding via a nasogastric tube.
  • The randomized trial included 52 patients (average age 77), comparing an isocaloric isoprotein formula (control group) against a diabetes-specific formula (experimental group).
  • Results showed that the experimental group had significantly fewer cases of hyperglycemia and a better rate of recovery via the oral route, but no differences in length of stay or mortality rates were observed.
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  • ALS is a progressive neurodegenerative disease associated with high rates of malnutrition, which can affect patient outcomes; this study aims to evaluate the effectiveness of muscle ultrasonography in identifying malnutrition and predicting prognosis in ALS patients.
  • The study analyzed 37 ALS patients using various methods to assess nutritional status, including anthropometric measurements and electrical bioimpedance analysis, alongside muscle ultrasonography of the quadriceps to evaluate both muscle mass and quality.
  • Results found that nearly 46% of patients were malnourished according to established criteria, with significant correlations between muscle mass measured by ultrasound and various markers of body composition, indicating the potential usefulness of muscle ultrasonography in ALS management.
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Objective: The aim of this study was to evaluate the impact of an enhanced ONS (enriched in EPA, DHA, leucine, and beta-glucans) on the dietary intake of cancer patients.

Methods: A randomized, double-blind, parallel, controlled, and multicenter clinical trial was conducted in patients with cancer and malnutrition. The trial compared prescribed dietary advice and two packs per day, for 8 weeks, of a hypercaloric (400 kcal/pack) and hyperproteic ONS (20 g/pack) with fiber and specific ingredients (leucine, EPA and DHA, and beta-glucans) (enhanced-ONS) versus an isocaloric and isoproteic formula (standard-ONS) without specific ingredients.

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Objectives: To propose the grounds for "diabetic sarcopenia" as a new comorbidity of diabetes, and to establish a muscle screening algorithm proposal to facilitate its diagnosis and staging in clinical practice.

Method: A qualitative expert opinion study was carried out using the nominal technique. A literature search was performed with the terms "screening" or "diagnostic criteria" and "muscle loss" or "sarcopenia" and "diabetes" that was sent to a multidisciplinary group of 7 experts who, in a face-to-face meeting, discussed various aspects of the screening algorithm.

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Objective: Despite the availability of a wide range of oral nutritional supplements (ONS) offerings, individuals with malnutrition are still struggling to meet their nutritional targets. A new concentrated and high-protein energy-dense ONS (≥2.1 kcal/mL;32 g protein/200 mL) with high-quality protein (60% whey protein) has emerged as a pivotal formula to reach the patient's energy-protein requirements, enhance compliance, and maximize stimulation of muscle protein synthesis, key factors driving better nutritional, functional, and clinical outcomes.

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Background: Progression diets after bariatric surgery (BS) are restricted in calories and protein, and they may induce a worsening of body composition. The aim of this study was to evaluate the effect of a modified diet with an oral nutritional supplement that is hyperproteic and normocaloric over the body composition.

Methods: A two-arm ambispective observational cohort study was designed.

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: The present study was designed to investigate SNP rs17300539 in the gene and its relationships with obesity, metabolic syndrome (MS), and serum circulating adiponectin. : The present design involved a Caucasian population of 329 subjects with obesity. Anthropometric and adiposity parameters, blood pressure, biochemical parameters, and the percentage of patients with metabolic syndrome were recorded.

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  • The SNP (rs3138167) is linked to metabolic disorders in obese individuals, and its impact on metabolic response post-diet intervention was unknown.
  • In a study of 1,008 obese Caucasians, those carrying the T allele showed higher levels of insulin and other markers compared to non-T allele carriers both before and after a 12-week hypocaloric Mediterranean diet.
  • Non-T allele carriers experienced significant improvements in metabolic markers like insulin and triglycerides, suggesting they had a better response to the dietary intervention than T allele carriers.
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Background and aims: some studies have reported links between 25-hydroxyvitamin D levels and the presence of metabolic syndrome. The aim of the present study was to evaluate whether an association exists among 25-hydroxyvitamin D, rs2282679 of the GC gene and metabolic syndrome (MS). Methods: the study involved a population of 134 postmenopausal obese females.

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Unlabelled: Nutritional ultrasonography is an emerging technique for measuring muscle mass and quality. The study aimed to evaluate the relationship between the parameters of body mass and quality of ultrasonography with other parameters of morphofunctional assessment in patients with disease-related malnutrition (DRM).

Methods: A cross-sectional study was developed on 144 patients diagnosed with DRM according to the Global Leadership Initiative on Malnutrition (GLIM) criteria.

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  • Hip fractures in patients aged 75 and older are highly disabling and often associated with malnutrition and sarcopenia, which is the loss of muscle mass and strength.
  • A study evaluated 186 patients hospitalized for hip fractures, revealing that 37.1% were at nutritional risk, 16.7% were malnourished, and a significant percentage of the patients had sarcopenia.
  • Results showed that patients with sarcopenia exhibited lower body mass index, older age, worse functional status, and greater disease burden, highlighting the interconnectedness of these conditions in older adults.
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Background And Aims: Medical oncology inpatients are at a very high risk of malnutrition, and the presence of complications associated with malnutrition is significant in their evolution. It is necessary to have adequate tools in the diagnosis of malnutrition.

Objectives: This study is aimed to assess the nutritional status of cancer inpatients and compare the incidence of complications based on the nutritional diagnosis with different tools.

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Nutritional ultrasound® is a new concept that uses ultrasound to assess body composition. It is composed of the evaluation of fat-free mass and fat mass. It is an emerging, economical, portable, non-invasive technique that evaluates the musculoskeletal area with linear, broadband, multifrequency probes, with a depth field of 20-100mm.

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Background: despite the relationship of resistin with metabolic syndrome (MS), the relationship of the 5'UTR intron C/T variant SNP rs7139228 of the RETN gene with the presence of MS has not been evaluated. Objective: the objective of this study is to evaluate the influence of SNP rs7139228 of the RETN gene on circulating resistin levels, as well as on MS in obese subjects. Material and Methods: a Caucasian population of 1003 obese subjects was enrolled.

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Objectives: an expert report is presented on the situation of loss of muscle mass in people with type 2 diabetes mellitus (T2DM), with a proposal of what the clinical approach to this comorbidity should be, based on the evidence from the literature and clinical experience. Method: a qualitative expert opinion study was carried out using the nominal approach. A literature search on diabetes and muscle was made and submitted to a multidisciplinary group of 7 experts who through a face-to-face meeting discussed different aspects of the role of muscle mass in T2DM.

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Introduction: rs822393 is related to dietary intervention responses. The aim of our study was to analyze the metabolic effects of 2 hypocaloric diets with a different fat profile during 3 months according to the genetic variant rs822393. Methods: a population of 361 obese patients were randomly allocated to one of two diets; Diet P (enriched in polyunsaturated fatty acids) vs.

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Background: some studies have evaluated the association of the rs1805134 genetic variant of the LEPR gene with obesity. Aims: the objective was to explore the association of the rs1805134 genetic variant of the LEPR gene with obesity measures and metabolic syndrome in obese Caucasian adults. Methods: we conducted a cross-sectional study in 212 obese subjects with body mass index (BMI) greater than 30 kg/m2.

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Introduction: Nutritional support in patients with COVID19 can influence the mean stay and complications in the patient in Intensive Care Unit (ICU).

Aims: To evaluate the selection of enteral nutritional treatment in the COVID-19 patient admitted to the ICU. To know the development of dysphagia and its treatment.

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Introduction: To evaluate the adequacy of TSH suppression therapy (TSHst) at the first disease assessment and the last follow-up visit.

Methods: Retrospective observational study of those patients under follow-up of DTC in a reference hospital.

Results: 216 patients (79.

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