Publications by authors named "Daniel Dahis"
Naturally occurring internal bleeding, such as in stomach ulcers, and complications following interventions, such as polyp resection post-colonoscopy, may result in delayed (5-7 days) post-operative adverse events-such as bleeding, intestinal wall perforation, and leakage. Current solutions for controlling intra- and post-procedural complications are limited in effectiveness. Hemostatic powders only provide a temporary solution due to their short-term adhesion to GI mucosal tissues (less than 48 h).
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- Safe and accurate delivery of biocompatible materials is essential for biomedical applications like drug release and tissue restoration, but current invasive methods pose risks such as infections and long healing times.
- A novel non-invasive method using acousto-sensitive materials allows for targeted delivery deep into the body by using ultrasound to polymerize materials without additional components.
- This technology not only enables controlled drug release and functional cell delivery but also allows for customization of material properties, paving the way for a new approach in clinical applications and 3D printing techniques, termed "acousto-printing."
Ultrasonic Thermal Monitoring of the Brain Using Golay-Coded Excitations-Feasibility Study.
IEEE Trans Ultrason Ferroelectr Freq Control
February 2022
Thermal monitoring during focused ultrasound (FUS) transcranial procedures is mandatory and commonly performed by MRI. Transcranial ultrasonic thermal monitoring is an attractive alternative. Furthermore, using the therapeutic FUS transducer itself for this task is highly desirable.
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- Multifunctional nanocarriers, specifically PLGA nanospheres with encapsulated CuO-NPs, hold promise for enhancing cancer treatment through antitumor activity and improved imaging capabilities.
- In vitro studies show that this delivery system enables controlled release of CuO-NPs, especially when stimulated by laser irradiation, facilitating localized treatment options.
- The research demonstrates that the combination of photothermal therapy with laser-triggered drug release using these nanocarriers can effectively target and treat head and neck cancer cells.
Speed of Sound and Attenuation Temperature Dependence of Bovine Brain: Ex Vivo Study.
J Ultrasound Med
June 2020
Article Synopsis
- Focused ultrasound (FUS) treatments for brain conditions require effective thermal monitoring to prevent tissue damage caused by heat, and this study investigates using ultrasound (US) for noninvasive temperature monitoring of brain tissues.
- Sixteen ex vivo bovine brain samples (7 white matter and 9 cortical matter) were heated and cooled while their speed of sound (SOS) and attenuation coefficient (AC) were measured using a computerized ultrasound system.
- The results indicate that SOS and AC respond to temperature changes in different brain tissues, suggesting potential for a US-based monitoring technique that could improve the accessibility and effectiveness of FUS treatments.