Publications by authors named "Daniel Czesla"

Article Synopsis
  • Patients may need dermatologic surgeries during pregnancy or breastfeeding, but there are often no established guidelines or approved drugs for these situations.
  • The article highlights common skin conditions treated surgically during these periods and outlines the specific precautions and risks involved.
  • While surgery can be done safely at any stage, the second trimester and right after delivery are the best times; immediate intervention is crucial for serious conditions like melanoma without causing delay for non-surgical treatments.
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The role of CXCR1, also known as fractalkine receptor, in hypertension is unknown. The present study determined the role of the fractalkine receptor CXCR1 in hypertensive renal and cardiac injury. Expression of CXCR1 was determined using CXCR1 mice that express a green fluorescent protein (GFP) reporter in CXCR1 cells.

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Adaptive and innate immune responses contribute to hypertension and hypertensive end-organ damage. Here, we determined the role of anaphylatoxin C5a, a major inflammatory effector of the innate immune system that is generated in response to complement activation, in hypertensive end-organ damage. For this purpose, we assessed the phenotype of C5a receptor 1 (C5aR1)-deficient mice in ANG II-induced renal and cardiac injury.

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