A new HLA-DRB allele (DRB1*15014) identified in a Caucasian individual.

Polymerase chain reaction with sequence specific primers subtyping of a DRB1*15 allele in a male 11-year-old German Caucasian and his father revealed a reaction pattern that did not agree with any known specificity, thus suggesting the existence of a novel allele. Sequence-based typing after allelic separation revealed the new allele human leukocyte antigen (HLA)-DRB1*15014. The sequence pattern of HLA-DRB1*15014 might have been generated as a result of two independent recombinations, most likely over several generations.