A navigated, robot-driven laser craniotomy tool for frameless depth electrode implantation. An recovery animal study.

We recently introduced a frameless, navigated, robot-driven laser tool for depth electrode implantation as an alternative to frame-based procedures. This method has only been used in cadaver and non-recovery studies. This is the first study to test the robot-driven laser tool in an recovery animal study.

Advanced cutting strategy for navigated, robot-driven laser craniotomy for stereoelectroencephalography: An non-recovery animal study.

In this study we aimed to present an updated cutting strategy and updated hardware for a new camera system that can increase cut-through detection using a cold ablation robot-guided laser osteotome. We performed a preoperative computed tomography scan of each animal. The laser was mounted on a robotic arm and guided by a navigation system based on a tracking camera.

STI in times of PrEP: high prevalence of chlamydia, gonorrhea, and mycoplasma at different anatomic sites in men who have sex with men in Germany.

Background: Men who have sex with men (MSM) are disproportionally affected by sexually transmitted infections (STI). STI are often extragenital and asymptomatic. Both can delay diagnosis and treatment.

Interferon Alpha Signalling and Its Relevance for the Upregulatory Effect of Transporter Proteins Associated with Antigen Processing (TAP) in Patients with Malignant Melanoma.

Introduction: Interferon alpha (IFNα) is routinely used in the clinical practice for adjuvant systemic melanoma therapy. Understanding the molecular mechanism of IFNα effects and prediction of response in the IFNα therapy regime allows initiation and continuation of IFNα treatment for responder and exclusion of non-responder to avoid therapy inefficacy and side-effects. The transporter protein associated with antigen processing-1 (TAP1) is part of the MHC class I peptide-loading complex, and important for antigen presentation in tumor and antigen presenting cells.

Sexual and reproductive health activities in HIV programmes: can we monitor progress?

Background: Resource allocation and integration of services have been of interest recently to achieve health-related Millennium Development Goals. This paper analyses the extent to which countries receiving funding in HIV were able to invest in activities in the area of sexual and reproductive health (SRH).

Methods: The authors screened the Global Fund grants data with an aggregate investment of US$16 billion in 140 countries to identify indicators revealing typical SRH services.

[Primary care in a detention environment].

Detention is a severe and psychologically traumatising form of withdrawal from society of people who, often, are already jeopardized or suffering from psychical or somatic diseases. Yet, the individual deprived of freedom has fundamental rights to obtain medical care that should be of equal quality than the general population. One of the numerous missions of the penitentiary practitioner is to fulfil his practice with total independence within a repressive environment, with multiple constraints of order, respecting both security and judiciary requirements and the fundamental ethical principles of penitentiary medicine.