Surveillance of the Antimicrobial Resistance Rates of Helicobacter pylori Ten Years Later in the Western Central Region, Colombia.

Background: Helicobacter pylori is a bacterium associated with gastroduodenal disease and gastric cancer. Empirical therapy in the treatment of H. pylori infection increases the risk of apparition of antimicrobial drug resistance.

Polymorphisms in oxidative pathway related genes and susceptibility to inflammatory bowel disease.

Aim: To investigate whether common variants in the oxidative pathway genes influence inflammatory bowel disease (IBD) risk among Moroccan patients.

Methods: The distribution of (TAAA)n_rs12720460 and (CCTTT)n _rs3833912 microsatellite repeats, -_rs11549467 and -94ins/delATTG_rs28362491 was analyzed in 507 subjects grouped in 199 IBD and 308 healthy controls. Genotyping was performed with polymerase chain reaction-fluorescent method and the TaqMan allelic discrimination technology.