Publications by authors named "Daniel A Gerardi"

Higher levels of exercise capacity and physical activity are desired outcomes in the comprehensive management of the COPD patient. In addition, improvements in exercise capacity and physical activity are instrumental to optimising other important therapeutic goals, such as improved health status, reduced healthcare utilisation and increased survival. Four general approaches towards increasing exercise capacity and physical activity in individuals with COPD will be discussed in this review: 1) pharmacological intervention, especially the administration of long-acting bronchodilators; 2) pulmonary rehabilitation, including exercise training and collaborative self-management; 3) behavioural interventions; and 4) web-based interventions.

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Article Synopsis
  • * Diagnosis involves procedures like bronchoalveolar lavage, which uncovers characteristic milky-opaque fluid and PAS-positive debris; defining treatment often targets the underlying condition, with lung lavage being an option for symptom relief.
  • * A case study details a 30-year-old woman with a history of myelodysplastic syndrome presenting with respiratory symptoms; she was diagnosed with secondary PAP after undergoing a bone marrow transplant, ultimately leading to resolution of her symptoms and improved lung health. *
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Angiosarcomas are malignant vascular tumors. Angiosarcomas arising in the thorax such as angiosarcoma of the lungs, heart and mediastinum are extremely rare. There are no reports of mediastinal angiosarcomas presenting with diffuse alveolar hemorrhage, which is a clinical syndrome characterized by the presence of hemoptysis, dyspnea, hypoxia, diffuse lung infiltrates and anemia.

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Objective: To discuss the nature of climate change and both its immediate and long-term effects on human respiratory health.

Methods: This review is based on information from a presentation of the American College of Chest Physicians course on Occupational and Environmental Lung Disease held in Toronto, Canada, June 2013. It is supplemented by a PubMed search for climate change, global warming, respiratory tract diseases, and respiratory health.

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Vitamin A derivative all-transretinoic acid (ATRA) has been reported to improve the outcome in patients with acute promyelocytic leukemia (APL). Retinoic Acid Syndrome (RAS) is a complication that has been noted to occur during the treatment of APL with ATRA. It is a clinical syndrome consisting of a constellation of signs and symptoms.

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