Development of a 3D printed chemiluminescence smartphone detector for high performance liquid chromatography.

A novel chemiluminescence detector for high-performance liquid chromatography (HPLC) was designed that incorporates a smartphone as photodetector, signal processor, and data storage unit. All detector components, including flow cell, flow cell holder, mixers, and housing, were fabricated by 3D printing and integration of the smartphone and 3D printed components provides a portable, low-cost, and user-friendly device. The detector was applied in the determination of carbamazepine using HPLC through a chemiluminescence reaction with tris(2,2'-bipyridyl)ruthenium(II) and cerium sulfate.

Smartphone as a fluorescence detector for high-performance liquid chromatography.

Fluorescence detection is employed in high-performance liquid chromatography (HPLC) due to its high specificity and sensitivity. However, it is often limited by expensive components and bulkiness. Recently, advances in technology and electronics have led to the development of smartphones that can serve as portable recording, analysis, and monitoring tools.

Batch Scale Production of 3D Printed Extraction Sorbents Using a Low-Cost Modification to a Desktop Printer.

This study reports a simple modification to a commercial resin 3D printer that significantly reduces the amount of prepolymer material needed for the production of extraction sorbents. The modified printing platform is demonstrated in the printing of two imidazolium-based ionic liquid (IL) monomers. Two geometries resembling a blade-type polymeric ionic liquid (PIL) sorbent used in thin-film microextraction and a fiber-type sorbent used in solid-phase microextraction (SPME) were printed.

Versatile dual-channel loop-mediated isothermal amplification assay featuring smartphone imaging enables determination of fecal indicator bacteria in environmental waters.

Rapid diagnostic assays are often a critical tool for monitoring water quality in developing and developed countries. Conventional testing requires 24-48 h for incubation, resulting in delayed remediation and increasing the likelihood of negative outcomes. In this study, we report a workflow for detection of E.

Digital Droplet Loop-Mediated Isothermal Amplification Featuring a Molecular Beacon Assay, 3D Printed Droplet Generation, and Smartphone Imaging for Sequence-Specific DNA Detection.

Nucleic acid detection is widely used in the amplification and quantitation of nucleic acids from biological samples. While polymerase chain reaction (PCR) enjoys great popularity, expensive thermal cyclers are required for precise temperature control. Loop-mediated isothermal amplification (LAMP) enables highly sensitive, rapid, and low-cost amplification of nucleic acids at constant temperatures.

Combination of paper-based thin film microextraction with smartphone-based sensing for sulfite assay in food samples.

Herein, a simple, green, and novel paper-based headspace-thin film microextraction in combination with smartphone-based on-cell detection was introduced. Sulfite was selected as a model compound to study the performance of the method. The method was based on converting sulfite to SO by acidification of the sample solution.