The Nephroprotective Activity of Rhizome by Reducing Creatinine, Urea Nitrogen, Glutamic Pyruvic Transaminase, and Malondialdehyde Levels in the Blood and Attenuating the Expression of , and Genes in the Kidney Cortex of Cisplatin-Induced Sprague-Dawley Rats.

Background: Cisplatin chemotherapy induces nephrotoxicity by producing reactive oxygen species, hence, discovering add-on nephroprotective drugs for patients with cancer is challenging. has been reported for its antioxidant properties.

Purpose: This study aims to explore the nephroprotective mechanism of the ethanol extract of rhizome (EEBR) in cisplatin-induced rats.