Publications by authors named "Dang Hoang Hiep"

Majonoside R2 (MR2), the principal saponin of Vietnamese ginseng ( Ha & Grushv.), has the unique structure of ocotillol-type dammarane and showed remarkable biological activities. This paper deals with the new findings in the chemical analysis MR2 by the tandem LC-MS/MS and, especially, its inhibitory activities on -glucosidase for diabetic management.

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Article Synopsis
  • Vietnamese ginseng (Panax vietnamensis) is well-known for its medicinal properties, particularly due to bioactive compounds called ginsenosides found mainly in its rhizome.
  • A recent study identified seven ginsenosides in the leaves of Vietnamese ginseng, notably ginsenoside Rd and pseudoginsenoside RS1, which showed significant inhibition of the enzyme acetylcholinesterase, important for memory function.
  • The research suggests that the leaves could be an alternative source for enhancing memory, providing a basis for further exploration into their potential anti-dementia benefits.
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A new benzophenanthridine alkaloid 6-butanoyldihydrochelerythrine and five known alkaloids 6-acetonyldihydronitidine , 6-acetonyldihydrochelerythrine , isocorydine , (O)-methyltembamide , N-(4-methoxyphenethyl)benzamide were isolated from the stem barks of . These structures were elucidated by 1D, 2D NMR spectroscopy and by mass spectrometry. This is the first time that compounds were identified from and the first time that compounds and were identified from the genus .

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