Kinesin-1 regulates synaptic strength by mediating the delivery, removal, and redistribution of AMPA receptors.

A primary determinant of the strength of neurotransmission is the number of AMPA-type glutamate receptors (AMPARs) at synapses. However, we still lack a mechanistic understanding of how the number of synaptic AMPARs is regulated. Here, we show that UNC-116, the C.