Analysis of the Improvement Effect of Nervonic Acid Extracted from Xanthoceras Sorbifolium Bunge Oil on Antioxidant Response and Inflammatory Response in Parkinson's Disease.

Objective: An extract of Xanthoceras sorbifolium Bunge (XSB) oil called nervonic acid (NA) was studied for its potential to ameliorate oxidative stress and inflammation in people living with Parkinson's disease (PD). Recrystallization column chromatography was performed to isolate NA from the XSB oil. Twenty-five C57BL/6 mice (8-10 weeks old) were randomly assigned to one of five groups (control, model, low, medium, and high dosage).

Berberine Inhibits Herpes Simplex Virus 1 Replication in HEK293T Cells.

Berberine exhibits polytrophic medicinal roles in various diseases and is safe and effective. However, its role and the underlying mechanism in the replication of herpes simplex virus 1 (HSV-1) remain unreported. This research aimed to determine the functional mechanisms of berberine on HSV-1 infection.

Nervonic acid amends motor disorder in a mouse model of Parkinson's disease.

[This retracts the article DOI: 10.1515/tnsci-2020-0171.].

Nervonic acid amends motor disorder in a mouse model of Parkinson's disease.

Objectives: Parkinson's disease (PD) is a kind of common neurodegenerative disease in the world. Previous studies have proved that nervonic acid (NA), extracted from Bunge, has the potentials of neuroprotection. However, the effect of NA on the PD remained unknown.