Publications by authors named "Danai Koftori"
Article Synopsis
- There is evidence that inhibitory killer cell immunoglobulin-like receptors (iKIRs) can influence T cell responses and survival, particularly in chronic viral infections.
- In a study with humans, it was found that individuals with more iKIR-ligand gene pairs had significantly longer-lasting memory CD8+ T cells, with lifespans increasing from 125 days to 250 days.
- The research suggests that iKIR-ligand genotypes play a crucial role in T cell survival and immune aging, independent of iKIR expression on the T cells themselves.
Human leukocyte antigen (HLA) B*51:01 and endoplasmic reticulum aminopeptidase 1 (ERAP1) are strongly genetically associated with Behçet's disease (BD). Previous studies have defined two subgroups of HLA-B*51 peptidome containing proline (Pro) or alanine (Ala) at position 2 (P2). Little is known about the unconventional non-Pro/Ala2 HLA-B*51-bound peptides.
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