Publications by authors named "Dana Todea-Iancu"
Article Synopsis
- The study explores the potential of single-wall carbon nanotubes (CNTs) not just as drug carriers, but as active anti-tumor agents that enhance the effects of traditional chemotherapy.
- Researchers treated cancer cells with CNTs and the drug etoposide, observing significant increases in anti-tumor activity when both were used together.
- The findings suggest that combining CNTs with chemotherapeutic drugs could lead to new, more effective cancer treatments by optimizing drug and material combinations for synergistic benefits.
Article Synopsis
- The study tested the delivery of functional nanomaterials, like gold and silver nanoparticles and carbon nanotubes, to two cell lines, showing quick uptake and significant changes in cell shape and size.
- The highest cell death was observed with carbon nanotubes, which increased with higher concentrations, indicating their strong impact on cellular health.
- Combining these nanomaterials with chemotherapy drugs dramatically increased cell death rates (100-300%), suggesting potential for new cancer treatments that use both types of agents together.
Host-related predictive factors for anastomotic leakage following large bowel resections for colorectal cancer.
J Gastrointestin Liver Dis
September 2008
Aim: To identify the risk, the host-related prognostic factors and their predictive value for anastomotic leakage after colorectal resections following cancer.
Method: 993 patients who underwent large bowel resection and primary anastomosis above 12 centimeters from the anal verge, without a temporary or permanent stoma at the Surgical Hospital No.3 (Cluj-Napoca, Romania) were retrospectively reviewed.
Purpose: We analyzed the clinical results of different techniques of resection for malignant colorectal (primary or staged) obstruction.
Methods: The subjects of this retrospective nonrandomized clinical study were 165 patients with malignant colorectal occlusion who underwent surgery treatment in our Department between 2002-2006. Patients with peritonitis or treated by means of permanent colostomy, palliative anastomosis, primary Hartman resection and rectal excision were excluded.
Bouveret syndrome associated with acute gangrenous cholecystitis.
J Gastrointestin Liver Dis
March 2008
An 89-year-old patient was hospitalized with signs of acute lithiasic cholecystitis and gastric emptying failure. The decision for surgery was taken and a subhepatic block was evidenced, caused by a perforated gangrenous cholecystitis with pericholecystic abscess, a cholecysto-antroduodenal fistula with two gallstones, 9/5 and 4/3 cm in size, impacted in the duodenum. It was necessary to perform an Y-en-Roux antroduodenojejunal anastomosis because an antroduodenal parietal defect resulted after the removal of the gangrenous gallbladder.
View Article and Find Full Text PDFBackground And Aim: Case selection criteria for resection of liver metastasis after colorectal cancer are still incompletely elucidated and represent a subject of great interest recently. Our aim was to evaluate 2-year survival after resection and to identify the survival risk and prediction factors in those cases.
Methods: 63 patients diagnosed and undergoing liver resection for colorectal metastatic disease to the liver at the Surgical University Hospital No.