Vaccination against tick-borne encephalitis (TBE) is based on the use of formalin-inactivated, culture-derived whole-virus vaccines. Immune response following vaccination is primarily directed to the viral envelope (E) protein, the major viral surface antigen. In Europe, two TBE vaccines are available in adult and pediatric formulations, namely FSME-IMMUN (Pfizer) and Encepur (GlaxoSmithKline).
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February 2007
Unlabelled: The Western blot (WB) method was verified for serological diagnosis of chlamydial infections.
Material And Methods: For testing, sera previously examined by the microimmunofluorescence (MIF) test with either ambiguous results or those suggesting persistent infection were used.
Results: Whereas the investigation confirmed adequate sensitivity and specificity of the MIF test for diagnosing Chlamydophila pneumoniae infection, it was less sensitive in case of Chlamydia trachomatis.