Publications by authors named "Dana Kimelman"

Purpose: While the literature has addressed the implementation of oncofertility care at developed institutions, minimal advice exists for those seeking to build oncofertility programs in limited resource settings (LRS). Our research offers a promising conversation on establishing oncofertility care in such settings from the perspective of a practitioner working to establish care in Latin America. We propose practices that have the potential to significantly improve access to and quality of care in these challenging settings.

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Objective: To report the first uterine transposition for fertility preservation in a patient with vulvar cancer.Case: A 26-year-old nulliparous patient with stage IIIB vulvar cancer, which was resected with adequate margins and bilateral inguinofemoral lymphadenectomy.Laparoscopic transposition of the uterus to the upper abdomen, outside of the scope of radiation was performed to preserve fertility and ovarian function.

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Advances in cancer treatments have determined an increase in survival rates. However, these lifesaving therapies may have a negative impact on reproductive health. To diminish the infertility risk; different fertility preservation strategies have been designed.

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Objective: To assess the relationship between maternal body mass index (BMI) and embryo morphokinetics on time-lapse microscopy (TLM).

Design: Retrospective cohort study.

Methods: All IVF cycles between June 2015 and April 2017 were reviewed.

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Article Synopsis
  • The Oncofertility Consortium is an international initiative focused on addressing the reproductive concerns of cancer patients, individuals transitioning genders, and others facing treatments that may affect fertility.
  • The consortium operates as a community of practice, sharing knowledge and strategies among specialists from various fields to improve healthcare outcomes and quality of life for patients.
  • Their ongoing mission is to combine scientific advancements with patient needs, aiming to create a supportive network that adapts to future challenges in reproductive health and survivorship.
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Objective: To use time-lapse imaging to compare embryo morphokinetic parameters between embryos resulting in euploid pregnancy loss and euploid embryos resulting in live birth.

Design: Retrospective cohort study.

Setting: Single academic fertility center.

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The high incidence of chromosome aneuploidy in human gametes and embryos is a major cause of in vitro fertilization (IVF) failure and miscarriage. In order to improve live birth rates with single embryo transfer, the use of preimplantation genetic testing for aneuploidy (PGT-A) has significantly increased. PGT encompasses methods that allow embryos to be tested for inherited conditions or screened for chromosomal abnormalities.

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Purpose: There is clinical evidence that early cleavage timing parameters predictive of blastocyst development also correlate with embryo implantation potential. The aim of this study is to determine the developmental competency of embryos with delayed blastulation.

Methods: Retrospective study performed from 2015 to 2016 at the Division of Reproductive Endocrinology and Infertility at Northwestern University.

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Purpose: Scientific literacy and communication are critical skills in the biological sciences. Journal clubs, in which peer-reviewed academic literature is discussed, are traditionally used to teach students to evaluate the literature, review scientific findings, and learn about historical, controversial, or current topics.

Methods: We used a virtual journal club to facilitate the international interaction between two universities with master's degree programs in the reproductive sciences: the University of Murcia (Spain) and Northwestern University (USA).

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Article Synopsis
  • This study looks at women who got pregnant through a special method called IVF with genetic testing called PGS and whether they did further testing for genetic problems early in their pregnancy.
  • Many women (about 73.5%) chose to do a safer type of testing instead of more invasive ones like amniocentesis.
  • The research showed that most women didn’t follow through with the recommended testing, and more studies are needed to understand why some decide not to do it, even after being informed about the risks and limitations.
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