Publications by authors named "Dana Bar-Ilan"

In this report, we describe the development of a reverse transcription-quantitative PCR (RT-qPCR) assay, termed Alpha-Delta assay, which can detect all severe acute respiratory syndrome coronavirus 2 (SC-2) variants and distinguish between the Alpha (B.1.1.

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The SARS-CoV-2 Lambda (Pango lineage designation C.37) variant of interest, initially identified in Peru, has spread to additional countries. First detected in Israel in April 2021 following importations from Argentina and several European countries, the Lambda variant infected 18 individuals belonging to two main transmission chains without further spread.

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Emerging SARS-CoV-2 (SC-2) variants with increased infectivity and vaccine resistance are of major concern. Rapid identification of such variants is important for the public health decision making and to provide valuable data for epidemiological and policy decision making. We developed a multiplex reverse transcriptase quantitative PCR (RT-qPCR) assay that can specifically identify and differentiate between the emerging B.

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Emerging SARS-CoV-2 variants may threaten global vaccination efforts and the awaited reduction in outbreak burden. In this study, we report a novel variant carrying the L452R mutation that emerged from a local B.1.

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Article Synopsis
  • Scientists investigated how SARS-CoV-2 spreads and identified viral variants using wastewater samples in Israel, showing it can effectively track virus prevalence across larger populations compared to traditional clinical methods.
  • The study, conducted from August 2020 to February 2021, sequenced 58 samples, revealing the emergence and spread of the B.1.1.7 variant in December 2020, even in areas with limited clinical testing.
  • The research highlights wastewater analysis as a valuable tool for monitoring the diversity of SARS-CoV-2 strains and detecting important mutations, which can inform public health strategies.
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The routine detection, surveillance, and reporting of novel SARS-CoV-2 variants is crucial, as these threaten to hinder global vaccination efforts. Herein we report a novel local variant with a non-synonymous mutation in the spike (S) protein P681H. This local Israeli variant was not associated with a higher infection rate or higher prevalence.

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The World Health Organization's Healthy Cities Network (HCN) enlists community stakeholders (residents, businesses, non-governmental organizations and municipal governments) to promote health, quality of life and sustainable development in urban settings. The project, now three decades old, involves thousands of municipalities globally, including 52 in Israel. However, there is very little evidence regarding the effects of joining the HCN.

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