Exploring neural mechanisms of gender differences in bodily emotion recognition: a time-frequency analysis and network analysis study.

Background: This study aimed to explore the neural mechanisms underlying gender differences in recognizing emotional expressions conveyed through body language. Utilizing electroencephalogram (EEG) recordings, we examined the impact of gender on neural responses through time-frequency analysis and network analysis to uncover gender disparities in bodily emotion recognition.

Methods: The study included 34 participants, consisting of 18 males and 16 females.

Current trends and hotspots of etiology of auditory neuropathy in the past 30 years: A bibliometric analysis.

Objective: To make an overview of global research trends in the etiology of auditory neuropathy (AN) over the past 30 years using a bibliometric approach.

Methods: Bibliometric analyses were conducted by GraphPad Prism 9.0, Citespace 6.

The nonpathogenic role of hyponatremia in the onset of osteoporosis: A Mendelian randomization study.

The relationship between hyponatremia and osteoporosis is controversial, and it remains unclear if there is a causal link between the two. This study employed a 2-sample Mendelian randomization (MR) analysis to investigate the potential causal relationship between hyponatremia and osteoporosis. The instrumental variables were derived from genome-wide association studies conducted in European populations.

Association between serum free fatty acids and gestational diabetes mellitus.

Background: Pregnant women with gestational diabetes mellitus (GDM) are at an increased risk of adverse pregnancy outcomes (APO). Early understanding of risk factors affecting these outcomes may facilitate preventive interventions for women at high risk. Blood samples from GDM and control pregnant women were collected for Free fatty acid (FFA) profiling to determine the relationship with the occurrence of APO in GDM pregnant women.

Engineered Mesenchymal Stem Cell-Derived Extracellular Vesicles Scavenge Self-Antigens for Psoriasis Therapy via Modulating Metabolic and Immunological Disorders.

Psoriasis is a chronic inflammatory dermatosis driven by excessive activation of the immune system. Recent studies have demonstrated the therapeutic potential of mesenchymal stem cell-derived extracellular vesicles (MSC-EVs) to psoriasis because of their immunomodulation functions. Yet, the outcome of MSC-EVs alone is still unsatisfactory and the underlying mechanisms are also unclear.

Infection of nonclassic monocytes by respiratory syncytial virus induces an imbalance in the CD4 T-cell subset response.

Respiratory syncytial virus (RSV) causes lower respiratory tract infections in infants and young children, leading to a pathogenesis-associated imbalance in CD4 T-cell subsets and monocyte subsets. To investigate whether RSV affects the imbalance of CD4 T-cells through monocytes, we examined the effects of the RSV-infected monocyte subset on CD4 T-cell subsets, namely, Th1, Th2, Th17, and regulatory T (Treg) subsets, on proliferation and identified key monocyte-derived cytokines. We found that RSV efficiently infects CD16 monocytes, but not CD16 monocytes, cocultures of CD4 T-cells with RSV-infected CD16 monocytes, inhibits Treg cell proliferation and increases Th2 cell frequency, suggesting that RSV causes an imbalance in the CD4 T-cell subset by primarily infecting CD16 monocytes.

Decreased Memory-Related Regional Cerebral Perfusion in Severe Obstructive Sleep Apnea with a Mild Cognitive Impairment During Wakefulness.

Purpose: Previous studies have found that obstructive sleep apnea (OSA) can induce cognitive impairment (CI). However, the exact mechanisms of CI development in patients with OSA remains unclear. We investigated the neuropathological basis of CI development by examining changes in cerebral blood perfusion.

Deciphering the atomistic mechanism underlying highly tunable piezoelectric properties in perovskite ferroelectrics via transition metal doping.

Piezoelectricity, a fundamental property of perovskite ferroelectrics, endows the materials at the heart of electromechanical systems spanning from macro to micro/nano scales. Defect engineering strategies, particularly involving heterovalent trace impurities and derived vacancies, hold great potential for adjusting piezoelectric performance. Despite the prevalent use of defect engineering for modification, a comprehensive understanding of the specific features that positively impact material properties is still lacking, this knowledge gap impedes the advancement of a universally applicable defect selection and design strategy.

Insight into the Local Surface Plasmon Resonance Effect of Pt-SnS Nanosheets in Tetracycline Photodegradation.

Constructing highly efficient catalysts for the degradation of organic pollutants driven by solar light in aquatic environments is a promising and green strategy. In this study, a novel hexagonal sheet-like Pt/SnS heterojunction photocatalyst is successfully designed and fabricated using a hydrothermal method and photodeposition process for photocatalytic tetracycline (TC) degradation. The optimal Pt/SnS hybrid behaves with excellent photocatalytic performance, with a degradation efficiency of 91.

Recent insights into RNA m5C methylation modification in hepatocellular carcinoma.

RNA 5-methylcytosine (m5C) methylation involves the addition of a methyl (-CH3) group to the cytosine (C) base within an RNA molecule, forming the m5C modification. m5C plays a role in numerous essential biological processes, including the regulation of RNA stability, nuclear export, and protein translation. Recent studies have highlighted the importance of m5C in the pathogenesis of various diseases, particularly tumors.

Injectable Polydopamine Nanoparticle-Incorporated Hydrogels for Antiangiogenesis and Stimulating Tumoricidal Immunity to Inhibit Metastasis and Recurrence Postresection.

Surgical resection is still the main means for clinical treatments of breast cancer, but the postoperative immunosuppressive microenvironment and neoangiogenesis of the residual tumors easily lead to tumor metastasis and recurrence, which will further endanger patients' lives. The combination of antiangiogenic therapy and immunotherapy may promote the mutually reinforced cycle of immune reprogramming and vascular normalization to avoid tumor metastasis and recurrence. Herein, we prepared polydopamine nanoparticles for improving tissue adhesion and enriching tumor-associated antigens.

Imaging of permeability defect distribution by electromagnetic tomography with hybrid L1 norm and nuclear norm penalty terms.

Electromagnetic tomography (EMT), with the advantages of being non-contact, non-invasiveness, low cost, simple structure, and fast imaging speed, is a multi-functional tomography technique based on boundary measurement voltages to image the conductivity distribution within the sensing field. EMT is widely used in industrial and biomedical fields. Currently, there are few studies on the application of EMT in magnetic permeability materials, which makes it difficult to obtain high-quality reconstructed images due to its own properties that lead to obvious attenuation of electromagnetic waves during propagation, as well as the ill-posed and ill-conditioned characteristics of EMT.

α-Linolenic acid promotes testosterone synthesis by improving mitochondrial function in primary rooster Leydig cells.

Unlabelled: The present study aimed to investigate the direct effects of α-Linolenic acid (ALA) on the in vitro production of testosterone and the expression of key enzymes and proteins related to steroidogenesis in Leydig cells of roosters.

Methods: Purified primary Leydig cells isolated from 65-week-old roosters were purified and treated with different concentrations of ALA treatments: (0 μm/L [control], solvent control group (DMSO), 20 μM/L, 40 μM/L, and 80 μM/L) and cell counting-8 (CCK-8) for cell viability assay, Enzyme-linked immunosorbent assay (ELISA) kit for the determination of testosterone in cell supernatants, quantitative (real-time) PCR, and analysis of activities of antioxidants catalase (CAT), superoxide dismutase (SOD) and malondialdehyde (MDA), evaluation of mitochondrial membrane potential, pro- and anti-apoptotic proteins/genes Bcl-2, Bcl-2-associated X protein (Bax), apoptosis-inducing factor (AIF) were done respectively.

Results: Our results showed that ALA significantly increased testosterone secretion in primary rooster Leydig cells (P < 0.

Resilience Development Among Adult Patients With De Novo Acute Leukemia: A Qualitative Study.

Objective: This study aimed to explore the development process of psychological resilience among adult patients with de novo acute leukemia.

Methods: This study utilized a descriptive qualitative approach, employing a purposeful sampling method to select a sample of 15 newly diagnosed patients with acute leukemia (AL) who underwent their initial induction chemotherapy treatment at the Hematology Department of the First Affiliated Hospital of Zhejiang University School of Medicine, China. Semi-structured interviews were conducted with the selected patients.

A Novel Concept for Cleavable Linkers Applicable to Conjugation Chemistry - Design, Synthesis and Characterization.

Linkers with disulfide bonds are the only cleavable linkers that utilize physiological thiol gradients as a trigger to initiate the intracellular drug release cascade. Herein, we present a novel concept exploiting the thiol gradient phenomena to design a new class of cleavable linker with no disulfide bond. To support the concept, an electron-deficient sulfonamide-based cleavable linker amenable to conjugation of drug molecules with targeting agents, was developed.

Effects of aged biochar additions at different addition ratios on soil greenhouse gas emissions.

Biochar addition is effective in reducing soil greenhouse gas (GHG) emissions, but it's essential to evaluate whether aged biochar retains this capability as its properties change over time. However, research comparing the effects of fresh and aged biochar on soil GHG emissions is limited. Moreover, exploring the priming effect of biochar on native soil organic carbon (SOC) mineralization is crucial for revealing the effect mechanism on soil CO emission.