Genome sequence of the hypervirulent ST65 Klebsiella pneumoniae isolate carrying mcr-8 from China.

Objective: In this study we report the complete genome sequence of a hypervirulent ST65 Klebsiella pneumoniae isolate harbouring mcr-8 from China. The aim was to investigate its molecular characteristics and resistance mechanisms.

Methods: Colistin-resistant hypervirulent K.

Phase I study of a non-S2P SARS-CoV-2 mRNA vaccine LVRNA009 in Chinese adults.

Background: COVID-19 caused by SARS-CoV-2 is a great threat to public health. We present the safety and immunogenicity data from a phase I trial in China of an mRNA vaccine (LVRNA009).

Methods: In the single-centre, double-blind, placebo-controlled and dose-escalation study, 72 healthy unvaccinated adults aged 18-59 years were randomized (3:1) to receive LVRNA009 with one of three vaccine dosage (25, 50 and 100 μg) or placebo, to evaluate for the safety, tolerability and immunogenicity of LVRNA009.

Preparation of bio-jet fuels by a controllable integration process: Coupling of biomass fermentation and olefin polymerization.

This work demonstrated that bio-jet fuels can be directionally prepared from bagasse (a typical lignocellulose biomass) by integrating bio- and chemical catalysis reaction processes. This controllable transformation started with the preparation of acetone/butanol/ethanol (ABE) intermediates through the enzymolysis and fermentation of bagasse. Pretreatment of bagasse by deep eutectic solvent (DES) promoted the enzymatic hydrolysis and fermentation because it destroyed the structure of biomass and remove lignin in lignocellulose.

Analytical Determination of Static Deflection Shape of an Asymmetric Extradosed Cable-Stayed Bridge Using Ritz Method.

A practical method to analyze the mechanical behavior of the asymmetric extradosed cable-stayed (AECS) bridge is provided in this paper. The work includes the analysis of the equivalent membrane tension of the cables, the ratio of side-span cable force to middle-span cable force, and the deflection of the main girder subject to uniformly distributed load. The Ritz method is a simple and efficient way to solve composite structures, such as the AECS bridge, compared with the traditional force method, displacement method, or finite element method.

The cubital tunnel syndrome caused by intraneural ganglion cyst of the ulnar nerve at the elbow: a case report.

Background: Cubital tunnel syndrome is common nerve compression syndrome among peripheral nerve compression diseases. However, the syndrome caused by intraneural ganglion cysts has been rarely reported. Medical approaches, like ultrasound-guided aspiration and open surgical treatment remain to be discussed.

Human cytomegalovirus and Epstein-Barr virus infections, risk factors, and their influence on the liver function of patients with acute-on-chronic liver failure.

Background: Studies on human cytomegalovirus (HCMV) and Epstein-Barr virus (EBV) have focused primarily on the immunosuppressed population. Few studies have considered immunocompetent and not severely immunocompromised patients. We determined the infection rates of HCMV and EBV, their risk factors and their influence on liver function in patients with HBV-related acute-on-chronic liver failure (ACLF).