Advancements in endohedral metallofullerenes: novel metal-cage interactions driving new phenomena and emerging applications.

Since the discovery of La@C, a wide array of endohedral metallofullerenes (EMFs) have been synthesized and documented. Various metals, including lanthanides, transition metals, alkali metals, alkaline earth metals and actinides, have been successfully incorporated into the inert fullerene cavities. The interaction between these encapsulated metal species and the fullerene cage isomers plays a crucial role in determining distinct molecular structures and imparting versatile chemical behaviors to these compounds.

Effects of high-frequency repetitive transcranial magnetic stimulation on the nutritional status of patients in a persistent vegetative state: A pilot study.

Purpose: This paper presents a preliminary study on whether repetitive transcranial magnetic stimulation (rTMS) can modulate the nutritional status of persistent vegetative state (PVS) patients (the primary endpoint) by regulating the intestinal flora and the metabolites, with the correlation between them also investigated.

Methods: Seventy-six patients with PVS were selected and divided into the observation group ( = 38) and the control group ( = 38) by random numerical grouping. All subjects' stool samples were examined for metabolites and analyzed regarding the short-chain fatty acids (SCFAs) content.

Visible-Light-Induced Alkylarylation of Unactivated Alkenes via Radical Addition/Truce-Smiles Rearrangement Cascade.

We disclosed a visible-light-induced alkylarylation reaction of unactivated alkenes via a metal-free radical addition/aryl translocation cascade sequence. Distal olefinic sulfonate was designed as a unique molecular scaffold allowing for a domino process to synthesize valuable alkylarylated alcohols in good yields with excellent diastereoselectivity, featuring mild reaction conditions, broad substrate scope, and excellent functional group tolerance. The mechanism investigation suggests that a visible-light-induced radical chain process dominates the cascade transformation.

Cyclin G2 promotes the formation of smooth muscle cells derived foam cells in atherosclerosis via PP2A/NF-κB/LOX-1 pathway.

Background: To investigate the role and underlying mechanism of cyclin G2 (G2-type cyclin) in the formation of vascular smooth muscle cells (VSMCs) derived foam cells.

Methods: The levels of α-SMA (alpha-SM-actin), p-NF-κB (phosphorylation nuclear transcription factors kappa B), and LOX-1 (lectin-like oxidized low-density lipoprotein receptor-1) were measured by immunohistochemistry and western blotting. The mouse aortic root smooth muscle cell line MOVAS was transfected to over-express cyclin G2, which were then stimulated with 80 µg/mL ox-LDL (oxidized low-density lipoprotein) to induce foam cell formation.

Effects of early intravenous low-dose of metoprolol on cardiac sympathetic activities and electrophysiological properties in myocardial infarction heart.

This study observed the effects of early intravenous low-doses of metoprolol on cardiac sympathetic activities and electrophysiological properties in myocardial infarction (MI) dogs. Thirty two mongrel dogs with the first diagonal branch of the left anterior descending coronary artery ligated were randomly divided into three groups: The low-dose group was given metoprolol 0.6 mg/kg immediately by intravenous injection (n=12); the target-dose group was given metoprolol 1.

Outcomes of percutaneous coronary intervention in patients ≥ 75 years: one-center study in a Chinese patient group.

Objective: To investigate the clinical and perioperative characteristics of patients ≥ 75 who undergoing percutaneous coronary intervention (PCI) and to evaluate the risk factors related to short-term post-PCI mortality in this specific patients group.

Methods: 1,035 consecutive subjects who underwent PCI from December 2011 to November 2013 were divided into four categories: (1) patients with stable angina (SA) ≥ 75 years (n = 58); (2) patients with SA < 75 years (n = 218); (3) patients with acute coronary syndrome (ACS) ≥ 75 years (n = 155); (4) patients with ACS < 75 years (n = 604). A multivariable logistic regression analysis was conducted to detect risk factors of six-month mortality in patients ≥ 75 years who had undergone PCI.

[Study of relationship between (Ca+Zn)/P of pure titanium surface coating and biological activity of osteoblasts].

Purpose: To study osteoblast (MC3T3-E1 cells) adhesion, proliferation and differentiation activity on the surface of pure titanium with different (Ca+Zn)/P ratios, and determine Ca, P, Zn contents offering best biological activity on pure titanium surface.

Methods: In the micro-arc oxidation electrolyte, Ca, P with a certain concentration, and 5 different concentrations of Zn (0, 0.01, 0.

[Study of relationship between different contents of zinc and antibacterial activity on calcium phosphate coating modified by plasma electrolytic oxidation method].

Purpose: Calcium phosphate activity coating containing different contents of zinc was deposited onto the surface of pure titanium modified by plasma electrolytic oxidation. The physical and chemical properties of different contents of zinc were compared among three groups, and the influence on antibacterial activity of P.gingivalis (Pg) and A.

[A clinical retrospective analysis of dental implants replaced in previously failed sites].

Purpose: To evaluate the clinical outcomes as well as related factors of dental implants replaced in previously failed sites.

Methods: A total of 12 patients (15 implants) who received replacement in previously failed sites during January 2005 to December 2011 were included. Outcomes of redo-implants were collected and clinical data was recorded and analyzed regarding risk factors related to redo-implants' survival using SPSS13.

[An assessment of different crown-to-implant ratio for implant teeth in the posterior region over 5 years].

Purpose: To evaluate the influence of crown-to-implant ratio (C/I ratio) on the results of restoration in the posterior region.

Methods: From January 2007 to January 2012,119 patients with 208 ITI implants in the posterior region were followed up for 6-66 months. Implant restorations were divided into three groups according to their respective clinical C/I ratios after noble porcelain-fused-to-mental crown restoration: C/I ≤1,1 View Article and Find Full Text PDF