Comprehensive bioinformatic analysis of the expression and prognostic significance of TSC22D domain family genes in adult acute myeloid leukemia.

Background: TSC22D domain family genes, including TSC22D1-4, play a principal role in cancer progression. However, their expression profiles and prognostic significance in adult acute myeloid leukemia (AML) remain unknown.

Methods: The online databases, including HPA, CCLE, EMBL-EBI, GEPIA2, BloodSpot, GENT2, UCSCXenaShiny, GSCALite, cBioportal, and GenomicScape, utilized the data of TCGA and GEO to investigate gene expression, mutation, copy number variation (CNV), and prognostic significance of the TSC22D domain family in adult AML.

[Response of Forest Ecosystems to Decreasing Atmospheric Nitrogen Deposition].

Nitrogen deposition has serious consequences to global change. Excessive nitrogen deposition leads to nitrogen saturation in forests, resulting in soil acidification, nitrate leaching, an increase in nitrous oxide emissions, and a decrease in plant species diversity and vegetation productivity. Under the reduction of atmospheric nitrogen deposition in Europe, North America, and China, summarizing the response of forests to decreasing nitrogen deposition can not only improve the knowledge framework of the impact of nitrogen deposition on forests, but also evaluate the effects of emission abatement actions, as well as provide scientific basis for future air pollution control.

[Distribution Characteristics of Heavy Metals in Farmland Soils Around Mining Areas and Pollution Assessment].

In order to explore the spatial distribution and ecological risk of heavy metals in farmland soil around Tongguan Mining area, surface soil samples from Tongguan Mining area were collected in September 2020, and the contents and distribution characteristics of eight heavy metals (Pb, Cu, Cd, Hg, Cr, Ni, Zn, and As) in the samples were analyzed. The Nemerow comprehensive pollution index and potential ecological risk index were used to evaluate soil pollution. The results showed that the contents of the eight types of heavy metal elements in this area exceeded the standard, and the exceeding rates were 97.

Evaluating γH2AX in spermatozoa from male infertility patients.

Objective: To investigate whether γH2AX levels were different in the spermatozoa of healthy men compared with infertility patients, and to assess the possible correlations between γH2AX and conventional semen parameters and double-stranded breaks (DSBs) identified with the use of comet assay.

Design: Prospective study.

Setting: Clinical laboratory.