Coxsackievirus A16 induced neurological disorders in young gerbils which could serve as a new animal model for vaccine evaluation.

Coxsackievirus A16 (CA16) is one of the major pathogens associated with human hand, foot, and mouth disease (HFMD) in the Asia-pacific region. Although CA16 infections are generally mild, severe neurological manifestations or even death has been reported. Studies on CA16 pathogenesis and vaccine development are severely hampered because the small animal models that are currently available show major limitations.

[Risk behavioral networks of newly reported HIV infections in Taizhou prefecture, Zhejiang province].

Objective: To understand the risk behavioral networks of newly reported HIV infections in Taizhou prefecture, Zhejiang province.

Methods: Newly reported HIV infections from May 2008 through March 2010 in Taizhou prefecture were invited to participate in a cross-sectional survey which requested numbers and contact information of individuals with whom they had had high risk contacts as well as risk behavioral acts with them. Persons having had risky contacts with HIV-infected cases were thereof approached to participate in this survey and to receive HIV testing.

[Human immunodeficiency virus/sexually transmitted infection, risk behavior and sexual networks among men who have sex with men in Taizhou city, Zhejiang province].

Objective: To study the prevalence of human immunodeficiency virus (HIV), sexually transmitted infection (STI), risk behavior and the sexual networks among men who have sex with men (MSM) in Taizhou city, Zhejiang province.

Methods: A cross-sectional study was applied with venue-based sampling in 2 MSM gathering sites in Taizhou. 'Informed Consent' principle was applied and MSM were studied through a structured questionnaire.