[A study on apoptosis and apoptotic mechanisms of HL-7702 cell line induced by methylmercury].

Objective: To study the apoptotic effect and mechanisms of methylmercury (MeHg) on HL-7702 cell line in vitro.

Methods: In this study, the cell apoptosis was observed by AO/EB method and FCM method; the mitochondrial membrane potential was detected by FCM; and the expression of proteins related to apoptosis was measured by immunocytochemical method.

Results: After exposure to MeHg for 24 h in different doses, apoptotic rate ascended with the increasing of MeHg concentration.