Publications by authors named "Dan-Yu Chen"

Article Synopsis
  • The study explores the relationship between total antioxidant capacity (T-AOC), glutathione peroxidase (GSH-PX), and advanced oxidized protein products (AOPP) levels in patients with nasopharyngeal carcinoma (NPC) undergoing radiotherapy, focusing on the development of oral mucositis (OM).
  • Researchers measured these biomarkers at various points during treatment and categorized patients into severe and non-severe OM groups to observe changes over time.
  • Findings indicate that while T-AOC and GSH-PX levels temporarily increased during treatment, they decreased significantly in severe OM patients, alongside consistently rising AOPP levels, with certain risk factors identified as contributing to the severity of OM.
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Background: Transgelin, an actin-binding protein, is associated with cytoskeleton remodeling. Findings from our previous studies demonstrated that transgelin was up-regulated in node-positive colorectal cancer (CRC) versus node-negative disease. Over-expression of affected the expression of 256 downstream transcripts and increased the metastatic potential of colon cancer cells in vitro and in vivo.

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A novel 65.8-kb multidrug resistance transposon, designated Tn, was characterized in a isolate from chicken in China. Tn contains 18 different antimicrobial resistance genes, including cephalosporinase gene and fluoroquinolone resistance genes and ' It carries a class 1/2 hybrid integron composed of and a 3' conserved segment of the class 1 integron.

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