Preparation and Properties of Sodium Carboxymethyl Cellulose Microspheres by Dropping Method.

Sodium carboxymethyl cellulose (CMC) is the most extensively utilized derivative of cellulose. In this study, an innovative approach was employed to disperse a CMC aqueous solution into olive oil in the form of liquid droplets, resulting in the direct formation of CMC microspheres after drying. The effects of CMC concentration and needle aperture size on microsphere formation were systematically investigated, showing that the particle size of the microspheres decreased with an increase in CMC concentration and a decrease in needle aperture.