[Ecological Responses of Soil Bacterial Communities to Heavy Metal Contamination Surrounding a Typical Coal-based Industrial Region].

Microbial communities in the soil might be affected by heavy metal contamination caused by anthropogenic activities associated with the coal-based industry. This study analyzed the differences in soil physicochemical properties, heavy metal concentrations, and enzyme activities surrounding different coal-based industrial fields(coal mining industry, coal preparation industry, coal-based chemical industry, and coal-fired power industry) in Shanxi Province, North China. Moreover, soil samples from farmland and parks away from all the industrial plants were collected as references.

Collagen VI-related myopathy with scoliosis alone: A case report and literature review.

Background: Scoliosis is a complex three-dimensional deformity of spine and one of the common complications of collagen VI-related myopathy, caused by mutations in (), , and genes. The typical clinical presentations of collagen VI-related myopathy include weakness, hypotonia, laxity of distal joints, contractures of proximal joints, and skeletal deformities.

Case Summary: A 28-year-old female presented with scoliosis for 28 years without weakness, hypotonia, laxity of distal joints, and contracture of proximal joints.

Aggressive Medulloblastoma-Derived Exosomal miRNAs Promote In Vitro Invasion and Migration of Tumor Cells Via Ras/MAPK Pathway.

Medulloblastomas (MBs) are currently divided into 4 molecular subgroups: WNT, SHH, Group 3, and Group 4. Among them, Group 3 MB has the worst prognosis, and 40%-50% of Group 3 cases are already metastatic at the time of diagnosis. Emerging evidence indicates that exosomes drive tumor invasion, but very little is known about exosomes in MBs.

Intraneural perineurioma affecting multiple nerves: a case report and literature review.

Intraneural perineurioma is a neoplasm of perineurial cells, corresponding to WHO grade I. We present a case of intraneural perineurioma affecting multiple nerves, which usually involved one or two of major nerve trunks in one patient. We describe the clinical presentation, magnetic resonance (MR) neurography characteristics, and pathological characteristics.

[Mutation of isocitrate dehydrogenase gene in Chinese patients with glioma].

Objective: To investigate mutation status of isocitrate dehydrogenase (IDH) 1 and IDH2 genes in Chinese patients with gliomas in correlation with clinicopathological characteristics.

Methods: Formalin-fixed and paraffin-embedded (FFPE) tissue samples of 234 gliomas were collected including the matched blood samples in 30 patients. DNA was extracted, followed by PCR-Sanger sequencing to detect IDH1 and IDH2 gene mutations.

[Improvement and application of diagnostic techniques of the skeletal muscle biopsy].

Objective: To summarize the improvement of various muscle staining techniques and discuss their application in diagnosis of neuromuscular diseases.

Methods: Three hundred cases of skeletal muscle biopsy samples were examined by histopathological methods. The flash-freezing techniques were used for the preparation of frozen section, which were stained with HE, Gomori trichromic (GMR), glycogen (PAS), and fat acid (oil red O); the enzyme histochemical staining with myosin adenosine triphosphatase (ATPase), and NADH-TR.