Utility of serum nuclear factor erythroid 2-related factor 2 as a potential prognostic biomarker of severe traumatic brain injury in adults: A prospective cohort study.

Objective: Nuclear factor erythroid 2-related factor 2 (Nrf2) may harbor endogenous neuroprotective role. We strived to ascertain the prognostic significance of serum Nrf2 in severe traumatic brain injury (sTBI).

Methods: This prospective cohort study included 105 controls and 105 sTBI patients, whose serum Nrf2 levels were quantified.

Two transporters mobilize magnesium from vacuolar stores to enable plant acclimation to magnesium deficiency.

Magnesium (Mg) is an essential metal for chlorophyll biosynthesis and other metabolic processes in plant cells. Mg is largely stored in the vacuole of various cell types and remobilized to meet cytoplasmic demand. However, the transport proteins responsible for mobilizing vacuolar Mg2+ remain unknown.

Nitrate Reductase-Mediated Nitric Oxide Regulates the Leaf Shape in by Mediating the Homeostasis of Reactive Oxygen Species.

As a gaseous biological signaling molecule, nitric oxide (NO) regulates many physiological processes in plants. Over the last decades, this low molecular weight compound has been identified as a key signaling molecule to regulate plant stress responses, and also plays an important role in plant development. However, elucidation of the molecular mechanisms for NO in leaf development has so far been limited due to a lack of mutant resources.

Trilogy, a Planetary Geodesy Mission Concept for Measuring the Expansion of the Solar System.

The scale of the solar system is slowly changing, likely increasing as a result of solar mass loss, with additional change possible if there is a secular variation of the gravitational constant, . The measurement of the change of scale could provide insight into the past and the future of the solar system, and in addition a better understanding of planetary motion and fundamental physics. Estimates for the expansion of the scale of the solar system are of order 1.

Effect of Qingxin Kaiqiao Fang on Hippocampus mRNA Expression of the Inflammation-Related Genes IL-1, GFAP, and A in an Alzheimer's Disease Rat Model.

Objective: To investigate the effects of QKF on expression of amyloid-beta (A), interleukin-1 beta (IL-1), and glial fibrillary acidic protein (GFAP) using a rat model of AD.

Materials And Methods: Fifty-six male Sprague-Dawley rats were randomly divided into seven groups (eight rats each): control group, sham-operated group, AD model group, groups of AD rats administered with low, medium, and high doses of QKF, and the donepezil group. AD was established by bilateral injection of -amyloid (A) 1-40 into the hippocampus.

Magnesium Transporter MGT6 Plays an Essential Role in Maintaining Magnesium Homeostasis and Regulating High Magnesium Tolerance in .

Magnesium (Mg) is one of the essential nutrients for all living organisms. Plants acquire Mg from the environment and distribute within their bodies in the ionic form via Mg-permeable transporters. In , the plasma membrane-localized magnesium transporter MGT6 mediates Mg uptake under Mg-limited conditions, and therefore is important for the plant adaptation to low-Mg environment.

Effects of microRNA-26b on proliferation and invasion of glioma cells and related mechanisms.

Neuroglioma is the most common primary malignant tumor in neurosurgery. Due to its short survival period and high patient mortality rate, neuroglioma is a major challenge in clinics. Elucidating the pathogenic mechanisms and associated molecular targets of neuroglioma can therefore benefit diagnosis and treatment of glioma.

Magnesium transporter AtMGT9 is essential for pollen development in Arabidopsis.

Magnesium (Mg(2+)) is abundant in plant cells and plays a critical role in many physiological processes. A 10-member gene family AtMGT (also known as AtMRS2) was identified in Arabidopsis, which belongs to a eukaryote subset of the CorA superfamily, functioning as Mg(2+) transporters. Some family members (AtMGT1 and AtMGT10) function as high-affinity Mg(2+) transporter and could complement bacterial mutant or yeast mutant lacking Mg(2+) transport capability.

AtMGT7: An Arabidopsis gene encoding a low-affinity magnesium transporter.

Magnesium (Mg(2+)) is one of the essential cations in all cells. Although the Mg(2+) transport mechanism has been well-documented in bacteria, less is known about Mg(2+) transporters in eukaryotes. The AtMGT gene family encoding putative magnesium transport proteins had been described previously.